Results 71 to 80 of about 4,175 (313)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

The relationship between photometric and spectroscopic oscillation amplitudes from 3D stellar atmosphere simulations. [PDF]

Mon Not R Astron Soc, 2021
Zhou Y, Nordlander T, Casagrande L, Joyce M, Li Y, Amarsi AM, Reggiani H, Asplund M.   +7 more
europepmc   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

The Radiation Environment of Exoplanet Atmospheres

Challenges, 2014
Exoplanets are born and evolve in the radiation and particle environment created by their host star. The host star’s optical and infrared radiation heats the exoplanet’s lower atmosphere and surface, while the ultraviolet, extreme ultraviolet and X ...
Jeffrey L. Linsky
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Star−Disk Collisions: Implications for Quasi-periodic Eruptions and Other Transients near Supermassive Black Holes

The Astrophysical Journal
We use Athena++ to study the hydrodynamics of repeated star−accretion disk collisions close to supermassive black holes, and we discuss their implications for the origin of quasi-periodic eruptions (QPEs) and other repeating nuclear transients.
Philippe Z. Yao, Eliot Quataert, Yan-Fei Jiang, Wenbin Lu, Christopher J. White   +4 more
doaj   +1 more source

Accretion shock stability on a dynamically heated YSO atmosphere with radiative transfer

EPJ Web of Conferences, 2014
Theory and simulations predict Quasi-Periodic Oscillations of shocks which develop in magnetically driven accretion funnels connecting the stellar disc to the photosphere of Young Stellar Objects (YSO).
de Sá Lionel, Chièze Jean-Pierre, Stehlé Chantal, Matsakos Titos, Ibgui Laurent, Lanz Thierry, Hubeny Ivan   +6 more
doaj   +1 more source

Physics of Stellar Atmospheres [PDF]

Nature, 1956
Physik der Sternatmospharen, mit besonderer Berucksichtigung der Sonne Zweite Auflage. Von Prof. A. Unsold. Pp. ix + 866. (Berlin: Springer-Verlag, 1955.) 168 D.M.
openaire   +2 more sources