Results 71 to 80 of about 43,149 (291)
, 2011 Context: Starbursts, and particularly their high-mass stars, play an essential role in the evolution of galaxies. The winds of massive stars not only significantly influence their surroundings, but the mass loss also profoundly affects the evolution of ...
Hoffmann, T. L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Stark Widths of Ar II Spectral Lines in the Atmospheres of Subdwarf B Stars
Atoms, 2017 Stark broadening parameters are of interest for many problems in astrophysics and laboratory plasmas investigation. Ar II spectral lines are observed in many kinds of stellar atmospheres such as the atmospheres of B-Type stars and subdwarf B stars.
Rafik Hamdi +3 more
doaj +1 more source
Stellar fluxes as probes of convection in stellar atmospheres [PDF]
Proceedings of the International Astronomical Union, 2006 AbstractConvection and turbulence in stellar atmospheres have a significant effect on the emergent flux from late-type stars. The theoretical advancements in convection modelling over recent years have proved challenging for the observers to obtain measurements with sufficient precision and accuracy to allow discrimination between the various ...
openaire +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Absolute Lineshifts - A new diagnostic for stellar hydrodynamics [PDF]
, 2003 For hydrodynamic model atmospheres, absolute lineshifts are becoming an observable diagnostic tool beyond the classical ones of line-strength, -width, -shape, and -asymmetry.
Dravins, Dainis
core +2 more sources
, 2018 Most galaxies comparable to or larger than the mass of the Milky Way host hot, X-ray emitting atmospheres, and many such galaxies are radio sources. Hot atmospheres and radio jets and lobes are the ingredients of radio-mechanical active galactic nucleus (
Churazov, E. +3 more
core +1 more source
Technetium in Stellar Atmospheres [PDF]
Symposium - International Astronomical Union, 1991 The quantitative determinations of technetium abundances are discussed. Up to now Tc abundances were found for nearly 30 stars which all are thermally pulsing AGB stars. The technetium abundance values for these AGB stars atmospheres, where it was found to be present, cluster around −1.0 ÷ 1.7.
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source