Results 71 to 80 of about 43,339 (292)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Limb Darkening and Planetary Transits: Testing Center-to-limb Intensity Variations and Limb-Darkening Directly from Model Stellar Atmospheres [PDF]

, 2017
The transit method, employed by MOST, \emph{Kepler}, and various ground-based surveys has enabled the characterization of extrasolar planets to unprecedented precision.
Ignace, Richard, Lester, John B., McNeil, Joseph T., Neilson, Hilding R.   +3 more
core   +3 more sources

On the Radiative Equilibrium of a Stellar Atmosphere. XIX.

The Astrophysical Journal, 1947
In this paper we tabulate the various H-functions which occur in the solutions of transfer problems involving Rayleigh's phase function and Rayleigh scattering (including the state of polarization of the scattered radiation). The H-functions have been determined numerically as the solutions of the exact functional equations which they satisfy.
S. Chandrasekhar, Frances H. Breen
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Stellar-flare-driven evolution of primordial early exo-Earth atmospheres: Insights from the young M dwarf flare model

Astronomy & Astrophysics
Context. M dwarfs are key targets for terrestrial exoplanet studies, with prospects for atmospheric spectroscopy. However, strong stellar magnetic activity and frequent flaring require modelling efforts to assess their impact on planetary atmospheres ...
Mamonova E., Herbst K., Kofman V., Ozgurel O., Kowalski A. F., Wedemeyer S., Werner S. C.   +6 more
doaj   +1 more source

Stellar masers, circumstellar envelopes, and supernova remnants

, 2007
This paper reviews recent advances in the study or circumstellar masers and masers found toward supernova remnants. The review is organized by science focus area, including the astrophysics of extended stellar atmospheres, stellar mass-loss processes and
Alvarez, Athol J. Kemball, Bessel, Colomer, Cotton, Cotton, Deguchi, Goss, Habing, Humphreys, Imai, Menten, Morris, Pardo, Sevenster, Sevenster, Sevenster, Soria-Ruiz, Szczerba, van Langevelde, Vlemmings, Vlemmings, Wittkowski, Yi   +23 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Stellar Radio Astronomy. Probing Stellar Atmospheres from Protostars to Giants

, 2002
Radio astronomy has provided evidence for the presence of ionized atmospheres around almost all classes of non-degenerate stars. Magnetically confined coronae dominate in the cool half of the Hertzsprung-Russell diagram.
Guedel, Manuel
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Radiation-driven winds of hot luminous stars. XVI. Expanding atmospheres of massive and very massive stars and the evolution of dense stellar clusters

, 2011
Context: Starbursts, and particularly their high-mass stars, play an essential role in the evolution of galaxies. The winds of massive stars not only significantly influence their surroundings, but the mass loss also profoundly affects the evolution of ...
Hoffmann, T. L., Pauldrach, A. W. A., Vanbeveren, D.   +2 more
core   +1 more source