Results 101 to 110 of about 276,873 (342)

The Breakthrough Listen Search for Intelligent Life: A Laser Search Pipeline for the Automated Planet Finder

open access: yesThe Astronomical Journal, 2023
The Search for Extraterrestrial Intelligence has traditionally been conducted at radio wavelengths, but optical searches are well-motivated and increasingly feasible due to the growing availability of high-resolution spectroscopy.
Anna Zuckerman   +6 more
doaj   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1269-1284, May 2025.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Automated Classification of Stellar Spectra using the Sloan Digital Sky Survey [PDF]

open access: yes, 2019
The classification of stellar spectra is a fundamental task in stellar astrophysics. There have been many explorations into the automated classification of stellar spectra but few that involve the Sloan Digital Sky Survey (SDSS).
Brice, Michael
core   +1 more source

The IACOB project XII. A new grid of northern standards for the spectral classification of B-type stars [PDF]

open access: yesA&A 690, A176 (2024)
With the advent of large spectroscopic surveys, automated stellar parameter determination has become commonplace. Nevertheless, spectral classification still offers a quick and useful alternative for obtaining parameter estimates for large samples of spectra of varying quality.
arxiv   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, Volume 599, Issue 7, Page 927-951, April 2025.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

ELUCID IV: Galaxy Quenching and its Relation to Halo Mass, Environment, and Assembly Bias

open access: yes, 2017
We examine the quenched fraction of central and satellite galaxies as a function of galaxy stellar mass, halo mass, and the matter density of their large scale environment.
Bosch, Frank C. van den   +19 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Classification of Astronomical Spectra Based on Multiscale Partial Convolution

open access: yesThe Astronomical Journal
The automated and efficient classification of astronomical spectra is an important research issue in the era of large sky surveys. Most current studies on automatic spectral classification primarily focus on specific data sets and demonstrate outstanding
Jingjing Wu   +5 more
doaj   +1 more source

Automated Classification of ELODIE Stellar Spectral Library Using Probabilistic Artificial Neural Networks [PDF]

open access: yesBull.Astron.Soc.India 36:1-54,2008, 2008
A Probabilistic Neural Network model has been used for automated classification of ELODIE stellar spectral library consisting of about 2000 spectra into 158 known spectro-luminosity classes. The full spectra with 561 flux bins and a PCA reduced set of 57, 26 and 16 components have been used for the training and test sessions.
arxiv  

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