Results 191 to 200 of about 220,453 (316)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Origins & Reservoirs of Exocomets. [PDF]

Space Sci Rev
Bannister M, Pfalzner S, Pearce T, Mustill AJ, Klahr H, Nomura H, Ohashi N, Kokotanekova R, Marino S, Bodewits D, Marschall R, Seligman DZ, Jones GH, Veras D.   +13 more
europepmc   +1 more source

First results from the TNG50 simulation: the evolution of stellar and gaseous discs across cosmic time [PDF]

, 2019
Annalisa Pillepich, Dylan Nelson, Volker Springel, Rüdiger Pakmor, Paul Torrey, Rainer Weinberger, Mark Vogelsberger, Federico Marinacci, Shy Genel, Arjen van der Wel, Lars Hernquist   +10 more
openalex   +1 more source

Two of the Binary Stellar Evolution Formation Channels

, 2023
Zhihan Yin
openalex   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A complex structure of escaping helium spanning more than half the orbit of the ultra-hot Jupiter WASP-121 b. [PDF]

Nat Commun
Allart R, Coulombe LP, Carteret Y, Splinter J, Dang L, Bourrier V, Lafrenière D, Albert L, Artigau É, Benneke B, Cowan NB, Doyon R, Krishnamurthy V, Jayawardhana R, Johnstone D, Langeveld AB, Meyer MR, Pelletier S, Piaulet-Ghorayeb C, Radica M, Taylor J, Turner JD.   +21 more
europepmc   +1 more source

The missing magnetic morphology term in stellar rotation evolution [PDF]

, 2016
Cecilia Garraffo, J. J. Drake, Ofer Cohen   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Coronal dimmings and what they tell us about solar and stellar coronal mass ejections. [PDF]

Living Rev Sol Phys
Veronig AM, Dissauer K, Kliem B, Downs C, Hudson HS, Jin M, Osten R, Podladchikova T, Prasad A, Qiu J, Thompson B, Tian H, Vourlidas A.   +12 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source