History of individual presolar SiC grains revealed by stellar winds. [PDF]
Bajo KI +4 more
europepmc +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Fundamentals of Interior Modelling and Challenges in the Interpretation of Observed Rocky Exoplanets. [PDF]
Baumeister P +9 more
europepmc +1 more source
Evolution of the anti-truncated stellar profiles of S0 galaxies since z = 0.6 in the SHARDS survey [PDF]
Alejandro Borlaff +9 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The Origins & Reservoirs of Exocomets. [PDF]
Bannister M +13 more
europepmc +1 more source
Chemical Abundances in Wolf-Rayet Ring Nebulae: Implications for Nucleosynthesis and Stellar Evolution [PDF]
C. Esteban
openalex +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Background-free <sup>12</sup>C(<i>α</i>, <i>γ</i>) angular distribution measurements with a time projection chamber operating in Gamma beams. [PDF]
Haverson KCZ +5 more
europepmc +1 more source

