Results 121 to 130 of about 3,795,687 (315)

On the Signature of Black Holes on the Quenched Stellar Mass Function

open access: yesThe Astrophysical Journal
As star-forming galaxies approach or exceed a stellar mass of around 10 ^11 M _⊙ , they are increasingly likely to be quenched in a process generically called mass quenching.
Antonio J. Porras-Valverde   +1 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Evidence that Mass Loss on the Red Giant Branch Decreases with Metallicity

open access: yesThe Astrophysical Journal
Mass loss on the red giant branch (RGB) influences stellar evolution, properties of stellar populations, and Galactic chemical enrichment, yet remains poorly constrained observationally. Current models provide limited insight into how stellar properties,
Yaguang Li
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Metallicities and Refined Stellar Parameters for 52 Cool Dwarfs with Transiting Planets and Planet Candidates

open access: yesThe Astrophysical Journal Supplement Series
We collected near-infrared spectra of 65 cool stars with the NASA Infrared Telescope Facility and analyzed them to calculate accurate metallicities and stellar parameters.
Rebecca Gore   +10 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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