Results 91 to 100 of about 2,874 (264)

Constraints on the Galaxy Formation Models during the Epoch of Reionization with High-redshift Observations

The Astrophysical Journal
We use high-resolution N -body dark matter simulations and L-G alaxies semianalytical galaxy formation models to explore the high- z galaxy properties and estimate the budget of ionizing photons.
Qing-Bo Ma, Xiao-Rong Chen, Ming Li, Qi Guo, Benedetta Ciardi, Anshuman Acharya, Xin Wang   +6 more
doaj   +1 more source

The importance of radiative feedback for the stellar initial mass function [PDF]

Monthly Notices of the Royal Astronomical Society, 2009
Published in MNRAS, 18 pages, 11 figures.
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Abundance Pattern Fitting with Bayesian Inference: Constraining First Stars’ Properties and Their Explosion Mechanism with Extremely Metal-poor Stars

The Astrophysical Journal
The abundance patterns of extremely metal-poor stars preserve a fossil record of the Universe’s earliest chemical enrichment by the supernova explosions from the evolution of first generation of stars, also referred to as Population III stars.
Ruizheng Jiang, Haining Li, Gang Zhao, Qianfan Xing, Wenyu Xin   +4 more
doaj   +1 more source

Understanding the Stellar Initial Mass Function

, 2006
The essential features of the stellar Initial Mass Function are, rather generally, (1) a peak at a mass of a few tenths of a solar mass, and (2) a power-law tail toward higher masses that is similar to the original Salpeter function. Recent work suggests that the IMF peak reflects a preferred scale of fragmentation associated with the transition from a
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

On the Determination of Stellar Mass and Binary Fraction of Open Clusters within 500 pc from the Sun

The Astrophysical Journal
We investigated the stellar mass function and the binary fraction of 114 nearby open clusters (OCs) using the high-precision photometric data from Gaia Data Release 3 (Gaia DR3).
Yueyue Jiang, Jing Zhong, Songmei Qin, Tong Tang, Li Chen, Jinliang Hou   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Big Galaxies and Big Black Holes: The Massive Ends of the Local Stellar and Black Hole Mass Functions and the Implications for Nanohertz Gravitational Waves

The Astrophysical Journal Letters
We construct the z = 0 galaxy stellar mass function (GSMF) by combining the GSMF at stellar masses M _* ≲ 10 ^11.3 M _⊙ from the census study of Leja et al.
Emily R. Liepold, Chung-Pei Ma
doaj   +1 more source