Results 81 to 90 of about 2,874 (264)

Measuring the stellar initial mass function [PDF]

Proceedings of the International Astronomical Union, 2019
AbstractThe birth of stars and the formation of galaxies are cornerstones of modern astrophysics. While much is known about how galaxies globally and their stars individually form and evolve, one fundamental property that affects both remains elusive.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Accessing the Host Galaxies of Long Gamma-Ray Bursts with Next-generation Telescopes

The Astrophysical Journal
We present a method to estimate the detection expectations of host galaxies of long gamma-ray bursts (LGRBs) in the grizJHKL bands. It is found that given the same limiting magnitude ${m}_{{grizJHKL},\mathrm{lim}}$ in each band, the z band produces the ...
Guang-Xuan Lan, Ye Li, Zhuo Li
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Measuring the Conditional Luminosity and Stellar Mass Functions of Galaxies by Combining the Dark Energy Spectroscopic Instrument Legacy Imaging Surveys Data Release 9, Survey Validation 3, and Year 1 Data

The Astrophysical Journal
In this investigation, we leverage the combination of the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys Data Release 9, Survey Validation 3, and Year 1 data sets to estimate the conditional luminosity functions and conditional ...
Yirong Wang, Xiaohu Yang, Yizhou Gu, Xiaoju Xu, Haojie Xu, Yuyu Wang, Antonios Katsianis, Jiaxin Han, Min He, Yunliang Zheng, Qingyang Li, Yaru Wang, Wensheng Hong, Jiaqi Wang, Zhenlin Tan, Hu Zou, Johannes Ulf Lange, ChangHoon Hahn, Peter Behroozi, Jessica Nicole Aguilar, Steven Ahlen, David Brooks, Todd Claybaugh, Shaun Cole, Axel de la Macorra, Biprateep Dey, Peter Doel, Jaime E. Forero-Romero, Klaus Honscheid, Robert Kehoe, Theodore Kisner, Andrew Lambert, Marc Manera, Aaron Meisner, Ramon Miquel, John Moustakas, Jundan Nie, Claire Poppett, Mehdi Rezaie, Graziano Rossi, Eusebio Sanchez, Michael Schubnell, Gregory Tarlé, Benjamin Alan Weaver, Zhimin Zhou   +44 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Surprisingly Similar: The Mass Function of Gaia Neutron Stars and Firstborn Double Neutron Stars

The Astrophysical Journal Letters
The mass distribution of neutron stars (NSs) encodes information about their formation and binary evolution. We compare the masses of two distinct populations: (I) the recently identified Gaia NSs in wide orbits with solar-like companions and (II) the ...
Aryanna Schiebelbein-Zwack, L. A. C. van Son, Maya Fishbach, Will M. Farr   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source