Results 111 to 120 of about 1,204,232 (364)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

An Expanded Set of Los Alamos OPLIB Tables in MESA: Type-1 Rosseland-mean Opacities and Solar Models

The Astrophysical Journal
We present a set of 1194 Type-1 Rosseland-mean opacity tables for four different metallicity mixtures. These new Los Alamos OPLIB atomic radiative opacity tables are an order of magnitude larger in number than any previous opacity table release, and span
Ebraheem Farag, Christopher J. Fontes, F. X. Timmes, Earl P. Bellinger, Joyce A. Guzik, Evan B. Bauer, Suzannah R. Wood, Katie Mussack, Peter Hakel, James Colgan, David P. Kilcrease, Manolo E. Sherrill, Tryston C. Raecke, Morgan T. Chidester   +13 more
doaj   +1 more source

Pulsation models of O-rich and C-rich long period variables

EPJ Web of Conferences, 2017
The intrinsic variability of luminous red giants is an observable providing important information about stellar structure and evolution. Our aim is to provide a solid theoretical background to the wide amount of data coming from present and future ...
Trabucchi Michele, Marigo Paola, Montalbán Josefina, Wood Peter R., Girardi Léo   +4 more
doaj   +1 more source

Model physics in low-mass solar-type stars: atomic diffusion and metallicity mixture

, 2018
Using asteroseismic data from the Kepler satellite, we explore the systematic uncertainties arising from changes in the input physics used when constructing evolution models of solar-type stars.
Campante, Tiago L., Cunha, Margarida S., Monteiro, Mário J. P. F. G., Nsamba, Benard, Reese, Daniel R., Rendle, Ben M., Verma, Kuldeep   +6 more
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Lux: A Generative, Multioutput, Latent-variable Model for Astronomical Data with Noisy Labels

The Astronomical Journal
The large volume of spectroscopic data available now and from near-future surveys will enable high-dimensional measurements of stellar parameters and properties. Current methods for determining stellar labels from spectra use physics-driven models, which
Danny Horta, Adrian M. Price-Whelan, David W. Hogg, Melissa K. Ness, Andrew R. Casey   +4 more
doaj   +1 more source

Observational clues to the physics at the magnetosphere in young stellar objects

EPJ Web of Conferences, 2014
Classical T Tauri stars offer an excellent laboratory to study the accretion process and star-disk interaction, which define the transfer of mass and angular momentum in the system. The interaction takes place very close to the star, in a region of about
Alencar Silvia H. P.
doaj   +1 more source

N-body simulations of gravitational dynamics

, 2011
We describe the astrophysical and numerical basis of N-body simulations, both of collisional stellar systems (dense star clusters and galactic centres) and collisionless stellar dynamics (galaxies and large-scale structure).
A. Ahmad, A. Brandt, A. Ishibashi, A. King, A. Klypin, A. Lenard, A. Sills, A. Sills, A. Tanikawa, A.V. Kravtsov, B. Lanzoni, B. Moore, B. Moore, C. Dupraz, C. Lajoie, C. Power, C. Theis, C.D. Bailyn, C.D. Bailyn, C.S. Frenk, D. Lynden-Bell, D. Pinchon, D. Sugimoto, D.C. Heggie, D.C. Heggie, D.C. Heggie, D.C. Heggie, D.J. Faulkner, D.J. Price, E. Athanassoula, E. Athanassoula, E. Gaburov, E. Holmberg, E. Kim, E. Kokubo, E. Komatsu, E. Terlevich, E.H. Morgan, F. Combes, F. Hohl, F.I. Cooperstock, G. Efstathiou, G. Efstathiou, G. Lodato, G.D. Quinlan, H. Baumgardt, H. Baumgardt, H. Baumgardt, H. Baumgardt, H. Baumgardt, H. Baumgardt, H. Cheng, H. Cohn, H. Yoshida, H. Yoshida, H.B. Perets, H.C. Plummer, I.A. Bonnell, I.T. Iliev, J. Dubinski, J. Dubinski, J. Heyvaerts, J. Magorrian, J. Magorrian, J. Makino, J. Makino, J. Makino, J. Makino, J. Makino, J. Stadel, J.E. Barnes, J.E. Barnes, J.E. Barnes, J.E. Greene, J.F. Navarro, J.G. Hills, J.K. Salmon, J.M. Fregeau, J.R. Hurley, K. Gebhardt, K. Gebhardt, K. Heitmann, K. Nitadori, K. Takahashi, L. Cullen, L. Greengard, L. Hernquist, L. Hernquist, L. Hernquist, L. Hernquist, M. Clutton-Brock, M. Davis, M. Freitag, M. Giersz, M. Hénon, M. Suzuki, M. Trenti, M. Volonteri, M. Zemp, M.B. Davies, M.D. Weinberg, M.D. Weinberg, M.S. Warren, N.N. Kozlov, P. Bode, P. Hut, P. Hut, P. Hut, P. Kustaanheimo, P. Madau, P. Saha, P. Saha, P.J. Quinn, P.J.E. Peebles, P.P. Ewald, Q. Sheng, R. Balescu, R. Klessen, R. Lynds, R. Spurzem, R. Spurzem, R. Teyssier, R.A. James, R.B. Larson, R.H. Miller, R.P. Church, R.P. Church, S. Chin, S. Ghigna, S. Harfst, S. Harfst, S. Inagaki, S. Mikkola, S. Mikkola, S. Mikkola, S. von Hoerner, S.D.M. White, S.D.M. White, S.D.M. White, S.F. Portegies Zwart, S.F. Portegies Zwart, S.F. Portegies Zwart, S.J. Aarseth, S.J. Aarseth, S.J. Aarseth, S.J. Aarseth, S.L.W. McMillan, T. Buchert, T. Fukushige, T. Holder, T. Ito, T.A. McGlynn, T.M. Éneev, V. Springel, V. Springel, V. Springel, V. Springel, V.F. Mukhanov, W. Dehnen, W. Dehnen, W. Dehnen, W. Priestley, W.D. Elliott, W.E. Harris   +163 more
core   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source