Results 131 to 140 of about 14,785 (302)
Far-ultraviolet Emission Line Investigation of Flares on AU Mic
The Astrophysical JournalThe role of nonthermal proton energy transportation during solar and stellar flares is largely unknown; a better understanding of this physical process will allow us to rectify longstanding deficiencies in flare models.
Adalyn Gibson +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
The Stagger Code for Accurate and Efficient, Radiation-coupled Magnetohydrodynamic Simulations
The Astrophysical JournalWe describe the Stagger code for simulations of magnetohydrodynamic (MHD) systems. This is a modular code with a variety of physics modules that will let the user run simulations of deep stellar atmospheres, sunspot formation, stellar chromospheres and ...
Robert F. Stein +3 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Molecular hydrogen in galaxies [PDF]
, 1987 This study aims to understand the key role played by molecular hydrogen in the evolution of galaxies, with a view to constraining its radial distribution in the Galaxy and the CO→H(_2) conversion factor α(_20).The star formation rate is shown to be ...
Wilkinson, David Adam, Wilkinson, D.A
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Gas-phase Oxygenation and Sulfurization Processes of Fullerene Cations
The Astrophysical JournalAtomic oxygen and sulfur are known to efficiently react with fullerenes and may thus form a long list of oxygenated and sulfurated fullerene species in the interstellar medium (ISM).
Nian Zhao +6 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source