Results 211 to 220 of about 68,538 (266)

Comprehensive Genetic and Molecular Characterization Confirms Hepatic Stellate Cell Origin of the Immortal Col-GFP HSC Line. [PDF]

open access: yesInt J Mol Sci
Buitkamp LF   +7 more
europepmc   +1 more source

TEAD4-mediated upregulation of LPAR3 augments hepatic stellate cell activation in portal hypertension. [PDF]

open access: yesCell Biol Toxicol
Qi R   +7 more
europepmc   +1 more source
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Cryopreservation of hepatic stellate cells

Journal of Hepatology, 2006
Isolated rat hepatic stellate cells (HSC) are taken as a valuable in vitro model to study hepatic fibrogenesis, biotransformation of pharmaceutics, gene expression, transcription factors controlling HSC behaviour, and for the establishment of long-term cultures. Consequently, methods for the isolation and maintenance of HSC cultures are well documented.
Svenja, Neyzen   +6 more
openaire   +2 more sources

Bile Acids and Stellate Cells

Digestive Diseases, 2015
Hepatic stellate cells are mainly known for their contribution to fibrogenesis in chronic liver diseases, but their identity and function in normal liver remain unclear. They were recently identified as liver-resident mesenchymal stem cells (MSCs), which can differentiate not only into adipocytes and osteocytes, but also into liver epithelial cells ...
Claus, Kordes   +3 more
openaire   +2 more sources

The Stellate Cell

1974
The stellate cells compose a class of small polymorphous neurons lying in the outer two thirds of the molecular layer. They were described by a number of early authors, FUSARI (1883), PONTI (1897), SMIRNOW (1897), in addition to RAMON YCAJAL (1889b), who in his great book on the nervous system (1911) gave SMIRNOW the credit for writing the most ...
Sanford L. Palay, Victoria Chan-Palay
openaire   +1 more source

Stellate cells in the digestive tract

Current Gastroenterology Reports, 2003
Although liver Sternzellen were initially described in 1876, it was not until the early 1970s that fat-storing cells, also called Ito cells or hepatic stellate cells (HSC), were demonstrated to be important sites of vitamin A storage. Subsequently, HSCs were found to be key players in the pathogenesis of hepatic fibrosis.
Reynaert, Hendrik   +3 more
openaire   +3 more sources

Stellate Cells in the Tumor Microenvironment

2020
As tumor microenvironments share many of the same qualities as chronic wounds, attention is turning to the wound-repair cells that support the growth of cancerous cells. Stellate cells are star-shaped cells that were first discovered in the perisinusoidal spaces in the liver and have been found to support wound healing by the secretion of growth ...
David, Roife   +2 more
openaire   +2 more sources

Vitamin A‐Storing Cells (Stellate Cells)

2007
Hepatic stellate cells (HSCs; also called as vitamin A-storing cells, lipocytes, interstitial cells, fat-storing cells, Ito cells) exist in the space between parenchymal cells and sinusoidal endothelial cells of the hepatic lobule, and store 80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm.
Haruki, Senoo   +2 more
openaire   +2 more sources

The diffuse stellate cell system

Journal of Molecular Histology, 2007
Hepatic stellate cells (HSCs) play an important role in liver fibrogenesis. Morphologically similar cells have been found at extrahepatic sites such as pancreas, kidney and colon. The true phenotypic relationship between these cells has not been fully established.
Zhao L, Burt AD
openaire   +3 more sources

Hepatic stellate cell: A star cell in the liver

The International Journal of Biochemistry & Cell Biology, 2009
Hepatic stellate cells represent a highly versatile cytotype that plays a significant role in liver development and differentiation, regeneration, xenobiotic response, immunoregulation, control of hepatic blood flow and inflammatory reactions. Because of the wide panel of molecular intermediates they may produce and secrete, particularly after their ...
ATZORI, LUIGI, Poli G, PERRA, ANDREA
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