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2015
Of all the different cell types in the pancreatic parenchyma, the most recently discovered cell is the pancreatic stellate cell (PSC). PSCs were first described more than 30 years ago, in 1982. Sixteen years later, in 1998, methods were developed to isolate and culture PSCs from the pancreas, which provided a much-needed impetus to studies on PSC ...
Minoti V. Apte +2 more
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Of all the different cell types in the pancreatic parenchyma, the most recently discovered cell is the pancreatic stellate cell (PSC). PSCs were first described more than 30 years ago, in 1982. Sixteen years later, in 1998, methods were developed to isolate and culture PSCs from the pancreas, which provided a much-needed impetus to studies on PSC ...
Minoti V. Apte +2 more
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American Journal of Physiology-Gastrointestinal and Liver Physiology, 1999
Although it has been hypothesized that contraction of hepatic stellate cells (HSC) regulates blood flow by modulating sinusoidal resistance, neither HSC contraction nor relaxation has been directly quantitated. To test this hypothesis, a force transducer was employed to directly measure the magnitude and rate of contraction and relaxation by primary ...
M S, Thimgan, H F, Yee
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Although it has been hypothesized that contraction of hepatic stellate cells (HSC) regulates blood flow by modulating sinusoidal resistance, neither HSC contraction nor relaxation has been directly quantitated. To test this hypothesis, a force transducer was employed to directly measure the magnitude and rate of contraction and relaxation by primary ...
M S, Thimgan, H F, Yee
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An Insight to Pituitary Folliculo‐Stellate Cells
Journal of Neuroendocrinology, 2008Folliculo‐stellate cells (FS‐cells) are star‐shaped and follicle‐forming cells in the anterior pituitary gland that were first identified by electron microscopy as non‐endocrine agranular cells. Light microscopy has revealed many of their cytophysiological features and the FS‐cell is known to be positive for S‐100 protein, a marker for FS‐cells. So far,
S, Devnath, K, Inoue
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1998
The hepatic stellate cell (HSC) has emerged as a major regulator of normal liver homeostasis and growth, as well as a key effector in the hepatic fibrogenic response. In this chapter, we review the biological characteristics of the hepatic stellate cell, addressing historical perspectives, morphologic characteristics, methods of isolation, and their ...
Victor Ankoma-Sey, Scott L. Friedman
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The hepatic stellate cell (HSC) has emerged as a major regulator of normal liver homeostasis and growth, as well as a key effector in the hepatic fibrogenic response. In this chapter, we review the biological characteristics of the hepatic stellate cell, addressing historical perspectives, morphologic characteristics, methods of isolation, and their ...
Victor Ankoma-Sey, Scott L. Friedman
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Stellate Cells and the Microcirculation
2011Activation of hepatic stellate cells (HSCs) within hepatic sinusoids during chronic liver diseases is a key feature of the capillarization of sinusoids. This latter feature likely represents an initial cause of portal hypertension during the early development of hepatic fibrosis.
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1999
In 1876, von Kupffer discovered star-shaped cells in the hepatic lobules using the gold chloride method, and called them “Sternzellen” (stellate cells). In 1898, however, he misconstrued these cells as phagocytic cells. The original stellate cells were rediscovered in 1971.
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In 1876, von Kupffer discovered star-shaped cells in the hepatic lobules using the gold chloride method, and called them “Sternzellen” (stellate cells). In 1898, however, he misconstrued these cells as phagocytic cells. The original stellate cells were rediscovered in 1971.
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2001
Carl Kupffer, by the use of a gold chloride staining method, detected in mammalian livers a population of stellate-shaped cells that were located perisinusoidally, always attached to the sinusoidal capillaries and also to the parenchymal cells (Kupffer 1876, cited by Wake 1980).
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Carl Kupffer, by the use of a gold chloride staining method, detected in mammalian livers a population of stellate-shaped cells that were located perisinusoidally, always attached to the sinusoidal capillaries and also to the parenchymal cells (Kupffer 1876, cited by Wake 1980).
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Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
Cell Metabolism, 2022Zhongmou Jin, Gautam Bandyopadhyay
exaly