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Cogent Medicine, 2019 Background: Human bone marrow has shown promise as a minimally invasive approach in treating a variety of musculoskeletal conditions due to the presence of stem cells, platelets, and growth factors in solution.
Marc Darrow +4 more
doaj +1 more source
Why regenerative stem cell medicine progresses slower than expected [PDF]
, 2014 Stem cell research has been acclaimed to revolutionize the future of medicine, and to offer new treatments for previously incurable diseases. Despite years of research, however, the therapeutic potential of stem cell research has not yet been fully ...
Amariglio +16 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Septins were first described in yeast. Due to extensive research in non-yeast cells, Septins are now recognized across all species as important players in the regulation of the cytoskeleton, in the establishment of polarity, for migration, vesicular trafficking and scaffolding.
Schuster, Tanja, Geiger, Hartmut
openaire +4 more sources
Distribution of interstitial stem cells in Hydra [PDF]
, 1979 The distribution of interstitial stem cells along the Hydra body column was determined using a simplified cloning assay. The assay measures stem cells as clone-forming units (CFU) in aggregates of nitrogen mustard inactivated Hydra tissue.
Bode +16 more
core +2 more sources
Stem cells supporting other stem cells [PDF]
Frontiers in Genetics, 2013 Adult stem cell therapies are increasingly prevalent for the treatment of damaged or diseased tissues, but most of the improvements observed to date are attributed to the ability of stem cells to produce paracrine factors that have a trophic effect on existing tissue cells, improving their functional capacity.
openaire +4 more sources
Stem cells in dermatology [PDF]
Anais Brasileiros de Dermatologia, 2014 Preclinical and clinical research have shown that stem cell therapy could be a promising therapeutic option for many diseases in which current medical treatments do not achieve satisfying results or cure. This article describes stem cells sources and their therapeutic applications in dermatology today.
Ogliari, Karolyn Sassi +3 more
openaire +6 more sources
Treatment of unresolved lower back pain with platelet-rich plasma injections
Cogent Medicine, 2019 Background: Platelet-Rich Plasma (PRP) is a non-invasive modality that has been used to treat musculoskeletal conditions for the past two decades. Based on our research, there were no publications that studied the effect of PRP on unresloved lower back ...
Marc Darrow +4 more
doaj +1 more source
Stem Cell Research & Therapy, 2016 Background The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or ...
Sapana Jalnapurkar +4 more
doaj +1 more source
PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development
Communications Biology, 2022 The transcription factor PU.1 recruits c-Jun as a co-activator to promoters without AP-1 binding sites, and mice with point mutations in PU.1 that disrupts the interaction between PU1 and c-Jun have defects in PU.1 dependent blood lineages, including ...
Xinhui Zhao +13 more
doaj +1 more source
An integrated gene regulatory network controls stem cell proliferation in teeth. [PDF]
, 2007 Epithelial stem cells reside in specific niches that regulate their self-renewal and differentiation, and are responsible for the continuous regeneration of tissues such as hair, skin, and gut.
Alonso, Maria T +9 more
core +4 more sources