Results 41 to 50 of about 2,605,751 (360)

Treatment of shoulder osteoarthritis and rotator cuff tears with bone marrow concentrate and whole bone marrow injections

open access: yesCogent Medicine, 2019
Background: Human bone marrow has shown promise as a minimally invasive approach in treating a variety of musculoskeletal conditions due to the presence of stem cells, platelets, and growth factors in solution.
Marc Darrow   +4 more
doaj   +1 more source

The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB [PDF]

open access: yes, 2017
Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor cell subpopulations. They differ from normal stem cells in the deregulation of the mechanisms that normally control stem cell ...
Carnero Moya, Amancio   +4 more
core   +1 more source

When is a stem cell really a stem cell? [PDF]

open access: yesBone Marrow Transplantation, 2003
While bone marrow transplantation has long been established as an effective approach to the clinical management of a variety of malignant and nonmalignant diseases, the future application of pluripotent stem cells in transplant settings promises to deliver this therapy to a much broader range of indications.
openaire   +3 more sources

Treatment of unresolved lower back pain with platelet-rich plasma injections

open access: yesCogent Medicine, 2019
Background: Platelet-Rich Plasma (PRP) is a non-invasive modality that has been used to treat musculoskeletal conditions for the past two decades. Based on our research, there were no publications that studied the effect of PRP on unresloved lower back ...
Marc Darrow   +4 more
doaj   +1 more source

Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts

open access: yesNature Communications, 2022
By coupling robotic cell culture systems with artificial intelligence–powered image analysis, Schiff et al. identify previously unseen characteristics of Parkinson’s disease in patient skin cells that distinguish them from healthy controls.
Lauren Schiff   +42 more
doaj   +1 more source

Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells

open access: yesStem Cell Research & Therapy, 2016
Background The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or ...
Sapana Jalnapurkar   +4 more
doaj   +1 more source

Advances in Recellularization of Decellularized Liver Grafts with Different Liver (Stem) Cells: Towards Clinical Applications

open access: yesCells, 2023
Liver transplantation is currently the only curative therapy for patients with acute or chronic liver failure. However, a dramatic gap between the number of available liver grafts and the number of patients on the transplantation waiting list emphasizes ...
Burak Toprakhisar   +2 more
doaj   +1 more source

Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA [PDF]

open access: yes, 2009
In Arabidopsis, the population of stem cells present in young flower buds is lost after the production of a fixed number of floral organs. The precisely timed repression of the stem cell identity gene WUSCHEL (WUS) by the floral homeotic protein AGAMOUS (
Das, Pradeep   +6 more
core   +2 more sources

Skeletal Stem Cells

open access: yesDevelopment, 2004
Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage, bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays. These lineages emerge in a specific sequence during embryonic development and post natal growth, and together comprise a continuous anatomical system, the bone-bone marrow ...
BIANCO, Paolo, P.G. Robey
openaire   +4 more sources

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. [PDF]

open access: yes, 2017
Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes are linked by the mitochondrial pyruvate carrier (MPC), which is required for efficient ...
A Ootani   +86 more
core   +1 more source

Home - About - Disclaimer - Privacy