Results 11 to 20 of about 817,109 (355)

Ocular surface microbiota: Ophthalmic infectious disease and probiotics

open access: yesFrontiers in Microbiology, 2022
Recently, increasing studies have emphasized the importance of commensal bacteria in humans, including microbiota in the oral cavity, gut, vagina, or skin.
Ming-Cheng Chiang   +2 more
doaj   +1 more source

Characteristics of the cancer stem cell niche and therapeutic strategies

open access: yesStem cell research & therapeutics, 2022
Distinct regions harboring cancer stem cells (CSCs) have been identified within the microenvironment of various tumors, and as in the case of their healthy counterparts, these anatomical regions are termed “niche.” Thus far, a large volume of studies ...
F. Ju   +8 more
semanticscholar   +1 more source

Hepatic stem cell niches [PDF]

open access: yesJournal of Clinical Investigation, 2013
Stem cell niches are special microenvironments that maintain stem cells and control their behavior to ensure tissue homeostasis and regeneration throughout life. The liver has a high regenerative capacity that involves stem/progenitor cells when the proliferation of hepatocytes is impaired.
Claus, Kordes, Dieter, Häussinger
openaire   +2 more sources

KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state

open access: yesJournal of Hematology & Oncology, 2021
Background Little is known about endogenous inhibitors of angiogenic growth factors. In this study, we identified a novel endogenous anti-angiogenic factor expressed in pericytes and clarified its underlying mechanism and clinical significance.
Jin-Woo Lee   +16 more
doaj   +1 more source

Artificial Stem Cell Niches [PDF]

open access: yesAdvanced Materials, 2009
AbstractStem cells are characterized by their dual ability to reproduce themselves (self‐renew) and specialize (differentiate), yielding a plethora of daughter cells that maintain and regenerate tissues. In contrast to their embryonic counterparts, adult stem cells retain their unique functions only if they are in intimate contact with an instructive ...
Matthias P, Lutolf, Helen M, Blau
openaire   +2 more sources

Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCs

open access: yesBiomaterials Research, 2023
Background Although vasospastic angina (VSA) is known to be caused by coronary artery spasm, no study has fully elucidated the exact underlying mechanism. Moreover, in order to confirm VSA, patients should undergo invasive coronary angiography with spasm
Han-Mo Yang   +14 more
doaj   +1 more source

Stem Cell Niche Microenvironment: Review [PDF]

open access: yesBioengineering, 2021
The cornea comprises a pool of self-regenerating epithelial cells that are crucial to preserving clarity and visibility. Limbal epithelial stem cells (LESCs), which live in a specialized stem cell niche (SCN), are crucial for the survival of the human corneal epithelium.
Mohamed Abdul-Al   +4 more
openaire   +4 more sources

The Vascular Stem Cell Niche [PDF]

open access: yesJournal of Cardiovascular Translational Research, 2012
Stem cells in adult organs reside in specialized niches that regulate their proliferation and differentiation. Investigations during the last few years have unveiled a regulatory role for blood vessels in these microenvironments. Mesenchymal stem cells (MSCs) are located surrounding capillaries in a variety of tissues and have the capacity to ...
Gómez-Gaviro, Maria Victoria   +3 more
openaire   +3 more sources

Root Stem Cell Niche networks: It's complexed! A review on gene networks regulating the Arabidopsis root stem cell niche.

open access: yesJournal of Experimental Botany, 2021
The presence of two meristematic cell populations in the root and shoot apex allow plants to grow indefinitely. Due to its simple and predictable tissue organisation, the Arabidopsis root apical meristem remains an ideal model to study mechanisms such as
Renan Pardal, R. Heidstra
semanticscholar   +1 more source

The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

open access: yeseLife, 2014
Mesenchymal stem cells (MSCs) and osteolineage cells contribute to the hematopoietic stem cell (HSC) niche in the bone marrow of long bones. However, their developmental relationships remain unclear.
Joan Isern   +7 more
doaj   +1 more source

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