Results 21 to 30 of about 193,899 (265)

Regenerative medicine for male infertility: A focus on stem cell niche injury models

open access: yesBiomedical Journal, 2022
Stem and progenitor cells located within stem cell niches maintain the renewal and regeneration of tissues and organs throughout the life of an adult organism.
Georgy Sagaradze   +5 more
doaj   +1 more source

Anatomical features and cell-cell interactions in the human limbal epithelial stem cell niche [PDF]

open access: yes, 2016
Epithelial stem cells of the ocular surface are essential for the maintenance of corneal transparency and therefore for vision. Human corneal/limbal epithelial stem cells (LESCs) are believed to reside in the limbus, the interface between the peripheral ...
Daniels, JT, Dziasko, MA
core   +1 more source

Interactions between induced pluripotent stem cells and stem cell niche augment osteogenesis and bone regeneration

open access: yesSmart Materials in Medicine, 2021
Repair and reconstruction of critical-size bone defects have been challenges in the clinic for many years. Stem cell therapy is a promising strategy for these dilemmas, and induced pluripotent stem cells (iPSCs) have emerged as competent candidates of ...
Zhangfan Ding   +4 more
doaj   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

open access: yes, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS   +3 more
core   +1 more source

Strategy to prime the host and cells to augment therapeutic efficacy of progenitor cells for patients with myocardial infarction

open access: yesFrontiers in Cardiovascular Medicine, 2016
Cell therapy in myocardial infarction (MI) is an innovative strategy that is regarded as a rescue therapy to repair the damaged myocardium and to promote neovascularization for the ischemic border zone.
Jeehoon Kang   +7 more
doaj   +1 more source

Exploring the origin of the cancer stem cell niche and its role in anti-angiogenic treatment for glioblastoma

open access: yesFrontiers in Oncology, 2022
Cancer stem cells are thought to be the main drivers of tumorigenesis for malignancies such as glioblastoma (GBM). They are maintained through a close relationship with the tumor vasculature.
Funto A. Akindona   +6 more
doaj   +1 more source

Advanced imaging and tissue engineering of the human limbal epithelial stem cell niche [PDF]

open access: yes, 2015
The limbal epithelial stem cell niche provides a unique, physically protective environment in which limbal epithelial stem cells reside in close proximity with accessory cell types and their secreted factors.
Daniels, JT   +10 more
core   +1 more source

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo [PDF]

open access: yes, 2017
Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (
Biondi, Andrea   +11 more
core   +2 more sources

Cellular population dynamics control the robustness of the stem cell niche

open access: yesBiology Open, 2015
Within populations of cells, fate decisions are controlled by an indeterminate combination of cell-intrinsic and cell-extrinsic factors. In the case of stem cells, the stem cell niche is believed to maintain ‘stemness’ through communication and ...
Adam L. MacLean   +2 more
doaj   +1 more source

Sensory nerves in the spotlight of the stem cell niche

open access: yesStem Cells Translational Medicine, 2021
Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life ...
Caroline C. Picoli   +13 more
doaj   +1 more source

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