Results 21 to 30 of about 817,109 (355)
Distant activation of Notch signaling induces stem cell niche assembly.
PLoS Genetics, 2021 Here we show that multiple modes of Notch signaling activation specify the complexity of spatial cellular interactions necessary for stem cell niche assembly.
Andriy S Yatsenko, Halyna R Shcherbata
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Stem Cell Research, 2015 We have previously shown that pluripotent stem cells can be induced from adult somatic cells which were exposed to protein extracts isolated from mouse embryonic stem cells (mESC).
Yoo-Wook Kwon +6 more
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Cell Reports, 2015 We investigate crosstalk between cancer cells and stromal myeloid cells. We find that Lewis lung carcinoma cells significantly induce PPARβ/δ activity in myeloid cells in vitro and in vivo.
Jonghanne Park +12 more
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Nature Communications, 2023 Aging associated defects within stem cell-supportive niches contribute towards age-related decline in stem cell activity. However, mechanisms underlying age-related niche defects, and whether restoring niche function can improve stem cell fitness, remain
Pradeep Ramalingam +9 more
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Journal of Biomedical Sciences, 2020 Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem cell niche has evolved with multifunctionality
Chih-Lung Chen +4 more
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Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
Nature Biomedical Engineering, 2020 Bone-marrow endothelial cells in the haematopoietic stem-cell niche form a network of blood vessels that regulates blood-cell traffic as well as the maintenance and function of haematopoietic stem and progenitor cells.
Marvin Krohn-Grimberghe +24 more
semanticscholar +1 more source
Stem Cell Research, 2014 The critical role that stem cell niches have in cardiac homeostasis and myocardial repair following injury is the focus of this review. Cardiac niches represent specialized microdomains where the quiescent and activated state of resident stem cells is regulated.
Annarosa Leri +4 more
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Headcase promotes cell survival and niche maintenance in the Drosophila testis. [PDF]
PLoS ONE, 2013 At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a self-renewal factor, Unpaired (Upd), that activates the JAK-STAT pathway in adjacent stem cells to ...
Luís Pedro F Resende +4 more
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The International Journal of Developmental Biology, 2005 Stem cells are required to support the indeterminate growth style of plants. Meristems are a plants stem cell niches that foster stem cell survival and the production of descendants destined for differentiation. In shoot meristems, stem cell fate is decided at the populational level.
Yvonne, Stahl, Rüdiger, Simon
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Regenerative medicine for male infertility: A focus on stem cell niche injury models
Biomedical Journal, 2022 Stem and progenitor cells located within stem cell niches maintain the renewal and regeneration of tissues and organs throughout the life of an adult organism.
Georgy Sagaradze +5 more
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