Results 11 to 20 of about 86,985 (264)
The SVZ stem cell niche–components, functions, and in vitro modelling
Frontiers in Cell and Developmental Biology, 2023 Neocortical development depends on the intrinsic ability of neural stem and progenitor cells to proliferate and differentiate to generate the different kinds of neurons in the adult brain.
Nesil Eşiyok, Michael Heide
doaj +1 more source
Notch signaling sculpts the stem cell niche
Frontiers in Cell and Developmental Biology, 2022 Adult stem cells depend on their niches for regulatory signaling that controls their maintenance, division, and their progeny differentiation. While communication between various types of stem cells and their niches is becoming clearer, the process of ...
Ana-Maria Zamfirescu +2 more
doaj +1 more source
eLife, 2014 Mesenchymal stem cells (MSCs) and osteolineage cells contribute to the hematopoietic stem cell (HSC) niche in the bone marrow of long bones. However, their developmental relationships remain unclear.
Joan Isern +7 more
doaj +1 more source
Distant activation of Notch signaling induces stem cell niche assembly.
PLoS Genetics, 2021 Here we show that multiple modes of Notch signaling activation specify the complexity of spatial cellular interactions necessary for stem cell niche assembly.
Andriy S Yatsenko, Halyna R Shcherbata
doaj +1 more source
Stem Cell Research, 2015 We have previously shown that pluripotent stem cells can be induced from adult somatic cells which were exposed to protein extracts isolated from mouse embryonic stem cells (mESC).
Yoo-Wook Kwon +6 more
doaj +1 more source
Cell Reports, 2015 We investigate crosstalk between cancer cells and stromal myeloid cells. We find that Lewis lung carcinoma cells significantly induce PPARβ/δ activity in myeloid cells in vitro and in vivo.
Jonghanne Park +12 more
doaj +1 more source
Nature Communications, 2023 Aging associated defects within stem cell-supportive niches contribute towards age-related decline in stem cell activity. However, mechanisms underlying age-related niche defects, and whether restoring niche function can improve stem cell fitness, remain
Pradeep Ramalingam +9 more
doaj +1 more source
Stem Cell Research, 2014 The critical role that stem cell niches have in cardiac homeostasis and myocardial repair following injury is the focus of this review. Cardiac niches represent specialized microdomains where the quiescent and activated state of resident stem cells is regulated.
Annarosa Leri +4 more
openaire +3 more sources
Headcase promotes cell survival and niche maintenance in the Drosophila testis. [PDF]
PLoS ONE, 2013 At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a self-renewal factor, Unpaired (Upd), that activates the JAK-STAT pathway in adjacent stem cells to ...
Luís Pedro F Resende +4 more
doaj +1 more source
The International Journal of Developmental Biology, 2005 Stem cells are required to support the indeterminate growth style of plants. Meristems are a plants stem cell niches that foster stem cell survival and the production of descendants destined for differentiation. In shoot meristems, stem cell fate is decided at the populational level.
Yvonne, Stahl, Rüdiger, Simon
openaire +3 more sources