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Stem cells supporting other stem cells [PDF]
Frontiers in Genetics, 2013 Adult stem cell therapies are increasingly prevalent for the treatment of damaged or diseased tissues, but most of the improvements observed to date are attributed to the ability of stem cells to produce paracrine factors that have a trophic effect on existing tissue cells, improving their functional capacity.
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Stem cells in dermatology [PDF]
Anais Brasileiros de Dermatologia, 2014 Preclinical and clinical research have shown that stem cell therapy could be a promising therapeutic option for many diseases in which current medical treatments do not achieve satisfying results or cure. This article describes stem cells sources and their therapeutic applications in dermatology today.
Ogliari, Karolyn Sassi +3 more
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When is a stem cell really a stem cell? [PDF]
Bone Marrow Transplantation, 2003 While bone marrow transplantation has long been established as an effective approach to the clinical management of a variety of malignant and nonmalignant diseases, the future application of pluripotent stem cells in transplant settings promises to deliver this therapy to a much broader range of indications.
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Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]
, 2016 Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai +3 more
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A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]
, 2019 Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes +9 more
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Proceedings of the National Academy of Sciences of the United States of America, 1981 This report describes the establishment directly from normal preimplantation mouse embryos of a cell line that forms teratocarcinomas when injected into mice. The pluripotency of these embryonic stem cells was demonstrated conclusively by the observation
G. Martin
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Current Biology, 2003 AbstractBritain is publicly and privately backing stem-cell research but worries continue about the legal framework scientists face in undergoing such work ...
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First steps to define murine amniotic fluid stem cell microenvironment [PDF]
, 2016 Stem cell niche refers to the microenvironment where stem cells reside in living organisms. Several elements define the niche and regulate stem cell characteristics, such as stromal support cells, gap junctions, soluble factors, extracellular matrix ...
Bertin, Enrica +11 more
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Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America, 2000 Dentinal repair in the postnatal organism occurs through the activity of specialized cells, odontoblasts, that are thought to be maintained by an as yet undefined precursor population associated with pulp tissue.
S. Gronthos +4 more
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Development, 2004 Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage, bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays. These lineages emerge in a specific sequence during embryonic development and post natal growth, and together comprise a continuous anatomical system, the bone-bone marrow ...
BIANCO, Paolo, P.G. Robey
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