Results 71 to 80 of about 1,421,854 (317)

Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts [PDF]

, 2012
Katrin Streckfuß‐Bömeke, Frieder Wolf, Azadeh Azizian, Michael Stauske, Malte Tiburcy, Stefan Wagner, Daniela Hübscher, Ralf Dressel, Simin Chen, Jörg Jende, Gerald Wulf, Verena Lorenz, Michael P. Schön, Lars S. Maier, Wolfram H. Zimmermann, Gerd Hasenfuß, Kaomei Guan   +16 more
openalex   +1 more source

Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss [PDF]

, 2020
Oyundari Amartuvshin, Chi‐Hung Lin, Shao‐Chun Hsu, Shih‐Han Kao, Alvin Chen, Wei‐Chun Tang, Hsin-Hung Chou, Dong‐Lin Chang, Yen‐Yang Hsu, Bai‐Shiou Hsiao, Elham Rastegari, Kun‐Yang Lin, Yuting Wang, Chi‐Kuang Yao, Guang‐Chao Chen, Bi‐Chang Chen, Hwei‐Jan Hsu   +16 more
openalex   +1 more source

Sox2 promotes tamoxifen resistance in breast cancer cells

EMBO Molecular Medicine, 2013
Development of resistance to therapy continues to be a serious clinical problem in breast cancer management. Cancer stem/progenitor cells have been shown to play roles in resistance to chemo‐ and radiotherapy.
Marco Piva, Giacomo Domenici, Oihana Iriondo, Miriam Rábano, Bruno M Simões, Valentine Comaills, Inmaculada Barredo, Jose A López‐Ruiz, Ignacio Zabalza, Robert Kypta, Maria d M Vivanco   +10 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells [PDF]

, 2015
Young Gie Chung, Shogo Matoba, Yuting Liu, Jin Hee Eum, Falong Lu, Wei Jiang, Jeoung Eun Lee, Vicken Sepilian, Kwang Yul, Dong Ryul Lee, Yi Zhang   +10 more
openalex   +1 more source

Direct fluorescence imaging of lignocellulosic and suberized cell walls in roots and stems [PDF]

, 2020
Peter Kitin, Satoshi Nakaba, Christopher G. Hunt, Sierin Lim, Ryo Funada   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta‐ defensin‐ 2 via toll‐ like receptor 4 signalling [PDF]

, 2015
Dong Kyung Sung, Yun Sil Chang, Se In Sung, Hye Soo Yoo, So Yoon Ahn, Won Soon Park   +5 more
openalex   +1 more source

Retracted: miR-100-5p Is a Novel Biomarker That Suppresses the Proliferation, Migration, and Invasion in Skin Cutaneous Melanoma

Stem Cells International, 2023
Stem Cells International
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source