Results 81 to 90 of about 13,488,362 (390)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Ankylosing spondylitis, chronic fatigue and depression improved after stromal vascular fraction treatment for osteoarthritis: a case report

Journal of Medical Case Reports, 2018
Background Osteoarthritis is a prevalent chronic disease that impacts quality of life and imposes a heavy economic burden. Despite this there is no confirmed treatment that could prevent progressive destruction of osteoarthritic joints.
Bora Bright, Ralph Bright, Pelin Bright, Amita Limaye   +3 more
doaj   +1 more source

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

Journal of Experimental Medicine, 1996
Hematopoietic stem cells (HSC) are multipotent cells that reside in the bone marrow and replenish all adult hematopoietic lineages throughout the lifetime of the animal.
M. Goodell, Katja Brose, Glenn A. Paradis, A. S. Conner, R. Mulligan   +4 more
semanticscholar   +1 more source

MicroRNAs, stem cells and cancer stem cells

World Journal of Stem Cells, 2012
This review discusses the various regulatory characteristics of microRNAs that are capable of generating widespread changes in gene expression via post translational repression of many mRNA targets and control self-renewal, differentiation and division of cells.
openaire   +3 more sources

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

Stem cell decisions:A twist of fate or a niche market? [PDF]

, 2014
Establishing and maintaining cell fate in the right place at the right time is a key requirement for normal tissue maintenance. Stem cells are at the core of this process.
Anderson, Barker, Bellis, Bettencourt-Dias, Bowman, Brawley, Buczacki, Cabernard, Cairns, Callaini, Cao, Carmena, Castanon, Castanon, Chen, Cheng, Chrétien, Clevers, Conduit, Conti, Das, Delgehyr, Doe, Du, Durand, Falconer, Gillies, Gonzalez, Goulas, Graser, Habib, Hotz, Hsu, Inke Näthke, Ishikawa, Izumi, Izumi, Januschke, Januschke, Januschke, Jauffred, Jens Januschke, Johnston, Juanes, Kai, Knoblich, Konno, Kouzarides, Lander, Lansdorp, Lechler, Lerit, Liakopoulos, Lim, Lu, Lu, Lécuyer, Mapelli, Merdes, Moore, Morin, Morin, Morrison, Neumüller, Nigg, Nipper, Ouellet, Paridaen, Pelletier, Pereira, Piel, Postiglione, Potten, Poulson, Quyn, Razafsky, Rebollo, Rebollo, Regan, Reiter, Rocheteau, Rogers, Rusan, Sato, Segalen, Segalen, Shaw, Shitamukai, Siller, Siller, Smith, Speicher, Tajbakhsh, Takeda, Tian, Tran, Vorobjev, Wall, Wang, Wang, Wang, Werts, Williams, Wu, Yadlapalli, Yadlapalli, Yamashita, Yamashita, Yamashita, Yennek, Yoshiura, Yu, Zou   +112 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations

Haematologica, 2020
Hematopoietic stem cells are responsible for life-long blood cell production and are highly sensitive to exogenous stresses. The effects of low doses of ionizing radiations on radiosensitive tissues such as the hematopoietic tissue are still unknown ...
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli   +9 more
doaj   +1 more source

Stemmed cells [PDF]

Current Biology, 2009
SummaryBritain's support for human-animal stem cell research seems to be faltering. Nigel Williams reports.
openaire   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source