Results 91 to 100 of about 2,855,746 (355)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Biological characteristics of Muse cells derived from MenSCs and their application in acute liver injury and intracerebral hemorrhage diseases

Regenerative Therapy
The increasing interest in multilineage differentiating stress-enduring (Muse) cells within the field of regenerative medicine is attributed to their exceptional homing capabilities, prolonged viability in adverse conditions, and enhanced three-germ ...
Han Li, Jinghui Wei, Mingzhi Li, Yaoqiang Li, Tong Zhang, Jialu Tian, Xuejia Liu, Kangjia Li, Juntang Lin   +8 more
doaj   +1 more source

Latest Developments in Early Detection and Effective Treatment of Cancer: A Meeting Report [PDF]

Cell Journal
Despite a lower estimated rate of cancer incidence in Iran compared to the global average, the trend is unfortunatelyincreasing. This necessitates the implementation of early detection of cancer and targeted therapies to effectively treatvarious types of
Morvarid Ghattan, Niloofar Bajool, Mina Pahlavanneshan, Melika Zamanian, Sharif Moradi   +4 more
doaj   +1 more source

Single cell transcriptome atlas of mouse mammary epithelial cells across development

Breast Cancer Research, 2021
Background Heterogeneity within the mouse mammary epithelium and potential lineage relationships have been recently explored by single-cell RNA profiling.
Bhupinder Pal, Yunshun Chen, Michael J. G. Milevskiy, François Vaillant, Lexie Prokopuk, Caleb A. Dawson, Bianca D. Capaldo, Xiaoyu Song, Felicity Jackling, Paul Timpson, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader   +12 more
doaj   +1 more source

Web Resources for Stem Cell Research

Genomics, Proteomics & Bioinformatics, 2015
Abstract In this short review, we have presented a brief overview on major web resources relevant to stem cell research. To facilitate more efficient use of these resources, we have provided a preliminary rating based on our own user experience of the overall quality for each resource. We plan to update the information on an annual basis.
Ting Wei, Xing Peng, Lili Ye, Jiajia Wang 0010, Fuhai Song, Zhouxian Bai, Guangchun Han, Fengmin Ji, Hongxing Lei   +8 more
openaire   +3 more sources

Isolation and characterisation of mouse amniotic fluid stem cells: study of their origin, regenerative potential and reprogramming into pluripotent cells [PDF]

, 2013
Introduction: Stem cells are defined by their ability to proliferate for a long period of time, a property known as ‘self-renewal’, and to give rise to differentiated cells.
Bertin, Enrica
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

PDK4 and nutrient responses explain muscle specific manifestation in mitochondrial disease

Clinical and Translational Medicine
Background Mitochondria elicit various metabolic stress responses, the roles of which in diseases are poorly understood. Here, we explore how different muscles of one individual—extraocular muscles (EOMs) and quadriceps femoris (QFs) muscles—respond to ...
Swagat Pradhan, Takayuki Mito, Nahid A Khan, Sofiia Olander, Aleksandra Zhaivoron, Thomas G McWilliams, Anu Suomalainen   +6 more
doaj   +1 more source

Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation

Cell Journal, 2018
Objective Dual inhibition of mitogen-activated protein kinase (MAPK) kinase (also known as MEK) and transforming growth factor β (TGFβ) type I receptors by PD0325901 and SB431542, known as R2i has been introduced as a highly efficient approach to the ...
Azam Samadian, Mahdi Hesaraki, Sepideh Mollamohamadi, Behrouz Asgari, Mehdi Totonchi, Hossein Baharvand   +5 more
doaj   +1 more source

Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation

, 2020
Background: The identification of endometrial stem/progenitor cells in a high turnover rate tissue suggests that a well-orchestrated underlying network controls the behaviour of these stem cells. The thickness of the endometrium can grow from 0.5-1 mm to
Ng, Ernest H Y, Chan, RWS, Chan, Rachel W S, Xu, Shan, Yeung, William S B, Li, T, Li, Tianqi, Ng, EHY, Yeung, WSB, Xu, S   +9 more
core   +1 more source