Results 91 to 100 of about 69,259,824 (258)

Prospects for Manipulation of Mesenchymal Stem Cells in Tumor Therapy: Anti-Angiogenesis Property on the Spotlight

, 2021
The interactions between the tumor microenvironment and the tumor cells confers a condition that accelerate or decelerate the development of tumor. Of these cells, mesenchymal stem cells (MSCs) have the potential to modulate the tumor cells.
Ghollasi, Marzieh, Korani, Mohsen, Ghasembaglou, Shahram, Asadi, Milad, Zarredar, Habib, Motallebnezhad, Morteza, Rahban, Dariush, Shahram Ghasembaglou, Marzieh Ghollasi, Milad Asadi, Morteza Motallebnezhad, Habib Zarredar, Mohsen Korani, Ali Salimi, Dariush Rahban   +14 more
core   +1 more source

Stem cell research and regenerative medicine: meeting report from the Royan International Stem Cell Congress 2025

Journal of Biological Engineering
The 21st Royan International Stem Cell Congress (3–5 September 2025, Tehran, Iran) convened the global stem cell community to assess the accelerating translation of regenerative medicine from bench to bedside.
Niloofar Bajool, Mehdi Abdolazimi, Mohsen Razzaznian, Zeinab Zakerian, Sharif Moradi   +4 more
doaj   +1 more source

Isolation, Characterization and Osteogenic Potential of Mouse Digit Tip Blastema Cells in Comparison with Bone Marrow- Derived Mesenchymal Stem Cells In Vitr

Cell Journal, 2017
Objective Limb regeneration mediated by blastema cells (BlCs) in mammals is limited to the digit tips of neonates. Due to the lack of access to BlCs in adults and the difficulty in isolating and expanding BlCs from neonates, the use of a cellular ...
Leila Taghiyar, Samaneh Hosseini, Mahdi Hesaraki, Forough Azam Sayahpour, Nasser Aghdami, Mohamadreza Baghban Eslami   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Treatment of Hypertrophic Scar in Human with Autologous Transplantation of Cultured Keratinocytes and Fibroblasts along with Fibrin Glue [PDF]

Cell Journal, 2015
Objective: Hypertrophic scar involves excessive amounts of collagen in dermal layer and may be painful. Nowadays, we can’t be sure about effectiveness of procedure for hypertrophic scar management.
Ehsan Taghiabadi, Parvaneh Mohammadi, Nasser Aghdami, Nasrin Falah, Zahra Orouji, Abdoreza Nazari, Saeed Shafieyan   +6 more
doaj  

In Vitro And In Vivo Comparison Of Different Types Of Rabbit Mesenchymal Stem Cells For Cartilage Repair

Cell Journal, 2019
Objective Systematic studies indicate a growing number of clinical studies that use mesenchymal stem cells (MSCs) for the treatment of cartilage lesions. The current experimental and preclinical study aims to comparatively evaluate the potential of MSCs
Mohammad Ali Khalilifar , Mohamadreza Baghaban Eslaminejad, Mohammad Ghasemzadeh, Samaneh Hosseini, Hossein Baharvand   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Uptake of synthetic low density lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategy [PDF]

, 2010
Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis.
Jørgensen, Heather G., Jorgensen, Heather G., Tessa L. Holyoake, Heather G. Jørgensen, Elliott, Moira A., Scobie, Linda, Crossan, Claire, Hatziieremia, Sophia, Zhou, Peixun; id_orcid, Elliott, Moira A, Sophia Hatziieremia, Michie, Alison M, Holyoake, Tessa L., Holyoake, Tessa L, Jørgensen, Heather G, Alison M. Michie, Halbert, Gavin W., Linda Scobie, Gavin W. Halbert, Moira A. Elliott, Claire Crossan, Michie, Alison M., Peixun Zhou, Halbert, Gavin W, Zhou, Peixun   +24 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source