Results 71 to 80 of about 54,707,328 (305)

Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation

Cell Journal, 2018
Objective Dual inhibition of mitogen-activated protein kinase (MAPK) kinase (also known as MEK) and transforming growth factor β (TGFβ) type I receptors by PD0325901 and SB431542, known as R2i has been introduced as a highly efficient approach to the ...
Azam Samadian, Mahdi Hesaraki, Sepideh Mollamohamadi, Behrouz Asgari, Mehdi Totonchi, Hossein Baharvand   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cardiac Specific Gene Expression Changes in Long Term Culture of Murine Mesenchymal Stem Cells [PDF]

, 2011
Murine MSCs are a readily available source of adult stem cells enabling extensive in vitro study of this cell population. MSCs have been described as multipotent, and have been proven capable of differentiation into several connective tissue types ...
Whitelaw, B., Argyle, S.A., Hodgkiss-Geere, H.M., Bennett, D., Argyle, D.J., Corcoran, B.M., Milne, E.   +6 more
core  

Sorting live stem cells based on Sox2 mRNA expression. [PDF]

, 2012
PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Hans M. Larsson (118208), Frey Peter, Larsson, H.M., Velluto, Diana, Hans M. Larsson, Jeffrey A. Hubbell (118232), Roccio Marta, Velluto Diana, Lee, S.T., Hubbell, Jeffrey A., Jeffrey A. Hubbell, Roccio, Marta, Peter Frey (118226), Lee, ST, Roccio, M, Matthias P Lutolf, Lutolf, MP, Velluto, D., Larsson, Hans M., Matthias P. Lutolf (118222), Lutolf, M.P., Frey, P., Larsson Hans M., Jeffrey A Hubbell, Seung Tae Lee, Lutolf Matthias P., Marta Roccio, Hubbell Jeffrey A., Larsson, HM, Velluto, D, Diana Velluto (118218), Peter Frey, Matthias P. Lutolf, Hubbell, JA, Lutolf, Matthias P., Hubbell, J.A., Lee Seung Tae, Roccio, M., Frey, Peter, Lee, Seung Tae, Marta Roccio (118214), Diana Velluto, Hans M Larsson, Seung Tae Lee (118211), Frey, P   +44 more
core   +3 more sources

Signs of immune dysregulation in second-trimester maternal blood RNA profiles in late-onset preeclampsia

Scientific Reports
Preeclampsia (PE) is a hypertensive disorder that affects 5% of pregnancies. It is characterized by new-onset hypertension and proteinuria after 20 weeks of gestation. We investigated maternal second-trimester peripheral blood gene expression profiles to
Gamze Yazgeldi Gunaydin, Sini Ezer, Juho Wedenoja, Katri Räikkönen, Juha Kere, Satu Wedenoja, Shintaro Katayama   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Isolation and characterisation of mouse amniotic fluid stem cells: study of their origin, regenerative potential and reprogramming into pluripotent cells [PDF]

, 2013
Introduction: Stem cells are defined by their ability to proliferate for a long period of time, a property known as ‘self-renewal’, and to give rise to differentiated cells.
Bertin, Enrica
core  

Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]

, 2011
Background: Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis.
St John, Justin, Kelly, Richard, Kelly, RDW, Stuart Egginton, Rae, Peter, Richard DW Kelly, StJohn, JC, Peter C Rae, St. John, Justin C., Justin C St John, Rae, Peter C., Egginton, Stuart, Rae, PC, Egginton, S, Kelly, Richard D. W., St John, JC   +15 more
core   +1 more source

Telomerase expression marks transitional growth-associated skeletal progenitor/stem cells: mTert marks skeletal progenitor/stem cells

, 2021
©2021 The Authors. Stem Cells published by Wiley Periodicals LLC on behalf of AlphaMed Press. Skeletal progenitor/stem cells (SSCs) play a critical role in postnatal bone growth and maintenance. Telomerase (Tert) activity prevents cellular senescence and
Tovaglieri, Alessio, Jiang, Lijie, Shah, Manasvi S, Breault, David T, Riba-Wolman, Rebecca D, Deary, Luke T, Mead, Benjamin E, Ambruzs, Dana M, Jaenisch, Rudolf, Carlone, Diana L, Lengner, Christopher J   +10 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source