Results 71 to 80 of about 4,949,444 (161)

Sorting live stem cells based on Sox2 mRNA expression. [PDF]

, 2012
PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Hans M. Larsson (118208), Frey Peter, Larsson, H.M., Velluto, Diana, Hans M. Larsson, Jeffrey A. Hubbell (118232), Roccio Marta, Velluto Diana, Lee, S.T., Hubbell, Jeffrey A., Jeffrey A. Hubbell, Roccio, Marta, Peter Frey (118226), Lee, ST, Roccio, M, Matthias P Lutolf, Lutolf, MP, Velluto, D., Larsson, Hans M., Matthias P. Lutolf (118222), Lutolf, M.P., Frey, P., Larsson Hans M., Jeffrey A Hubbell, Seung Tae Lee, Lutolf Matthias P., Marta Roccio, Hubbell Jeffrey A., Larsson, HM, Velluto, D, Diana Velluto (118218), Peter Frey, Matthias P. Lutolf, Hubbell, JA, Lutolf, Matthias P., Hubbell, J.A., Lee Seung Tae, Roccio, M., Frey, Peter, Lee, Seung Tae, Marta Roccio (118214), Diana Velluto, Hans M Larsson, Seung Tae Lee (118211), Frey, P   +44 more
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Precise Correction of Lhcgr Mutation in Stem Leydig Cells by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice. [PDF]

Adv Sci (Weinh), 2023
Xia K, Wang F, Tan Z, Zhang S, Lai X, Ou W, Yang C, Chen H, Peng H, Luo P, Hu A, Tu X, Wang T, Ke Q, Deng C, Xiang AP.   +15 more
europepmc   +1 more source

Bisphenol A stimulates differentiation of rat stem Leydig cells in vivo and in vitro

Molecular and Cellular Endocrinology, 2018
Bisphenol A (BPA) is widely used in consumer products and a potential endocrine disruptor linked with sexual precocity. However, its action and underlying mechanisms on male sexual maturation is unclear. In the present study, we used a unique in vivo ethane dimethane sulfonate (EDS)-induced Leydig cell regeneration model that mimics the pubertal ...
Lanlan Chen, Yu Zhao, Linchao Li, Lubin Xie, Xianwu Chen, Jianpeng Liu, Xiaoheng Li, Lixu Jin, Xingwang Li, Ren-Shan Ge   +9 more
openaire   +3 more sources

Stem cells in the ovary [PDF]

, 2009
For decades, scientists have thought that female mammals are born with a lifetime supply of oocytes in the ovary, irreversibly destined to decline after birth.
Tomaszczuk-Kossowska, Katarzyna
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Role of p57KIP2 in Stem and Progenitor Leydig Cells of Mouse Testes

The World Journal of Men's Health
Precise control of proliferation and differentiation of Leydig cells is important for gonadal androgenesis and spermatogenesis. Though cyclin-dependent kinase inhibitors are crucial for cell proliferation and differentiation, their role in the development of early adult Leydig cells (ALCs) remained unanswered.
Seung Hyun Park, Kyung Noh Yoon, Yang Xu, Myung Chan Gye   +3 more
openaire   +3 more sources

Reconstructing the Stem Leydig Cell Niche via the Testicular Extracellular Matrix for the Treatment of Testicular Leydig Cell Dysfunction

Advanced Science
AbstractTherapies involving the use of stem Leydig cells (SLCs), as testicular mesenchymal stromal cells, have shown great promise in the treatment of Leydig cell (LC) dysfunction in aging males. However, the outcomes of these therapies are not satisfactory.
Ani Chi, Chao Yang, Jie Liu, Zhichen Zhai, Xuetao Shi   +4 more
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Stem Cell Factor Functions as a Survival Factor for Mature Leydig Cells and a Growth Factor for Precursor Leydig Cells after Ethylene Dimethane Sulfonate Treatment: Implication of a Role of the Stem Cell Factor/c-Kit System in Leydig Cell Development

Developmental Biology, 2000
The significance of the interaction between Sertoli cell-produced stem cell factor (SCF) and its receptor, c-kit, on Leydig cells (LCs) during LC development and differentiation is unknown. In the present study, we investigated the potential role of the SCF/c-kit system in LC apoptosis and precursor LC proliferation after ethylene dimethane sulfonate ...
Yan, Wei, Kero, Jukka, Huhtaniemi, Ilpo, Toppari, Jorma   +3 more
openaire   +2 more sources

Purification of Immature Neuronal Cells from Neural Stem Cell Progeny [PDF]

Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications.
Brent A Reynolds, اسفندياري, ابراهيم, Reynolds, Brent A, Maryam Rahman, Osborne, Geoffrey W, Dennis A Steindler, Adams, David J, Dennis A. Steindler, Takahiro Yasuda, Bjorn Scheffler, Brent A. Reynolds, Scheffler, Bjorn, Mohammad G Golmohammadi, گل محمدی, محمد قاسم, Geoffrey W Osborne, Hassan Azari, David J. Adams, Mohammad G. Golmohammadi, Deleyrolle, Loic P, Steindler, Dennis A, Ebrahim Esfandiari, Loic P Deleyrolle, آذری, حسن, Yasuda1, Takahiro, رحمان, مریم, David J Adams, Loic P. Deleyrolle, Geoffrey W. Osborne   +27 more
core   +2 more sources

Use of in vitro methodology to investigate phthalate effects on the differentiation of seminiferous tubule-associated stem cells to form Leydig cells and on the Leydig cells derived from the stem cells

Frontiers in Toxicology
Introduction: Leydig cells isolated from the testis are able to sustain high levels of testosterone production in vitro, but only for up to 3 days. Such cells are valuable for addressing the acute effects of chemicals on steroidogenic function, but not for repeated or chronic effects.
Kassim Traore, Kassim Traore, Barry Zirkin   +2 more
openaire   +3 more sources

Investigating the properties of cancer stem cells and epithelial to mesenchymal transition in human prostate cancer [PDF]

, 2012
In recent years, the cancer stem cell hypothesis has emerged as a compelling but controversial model of cancer progression. Contrary to the clonal evolution model, the cancer stem cell hypothesis postulates that, akin to normal tissues, tumours are ...
Dunning-Foreman, NL
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