Results 121 to 130 of about 177,307 (324)

Preparation of 4 '-spirocyclobutyl nucleoside analogues as novel and versatile adenosine scaffolds

, 2019
Despite the large variety of modified nucleosides that have been reported, the preparation of constrained 4 '-spirocyclic adenosine analogues has received very little attention.
De Vleeschouwer, Freija, Kong, Hanchu, Meerpoel, Lieven, Pande, Vineet, Sun, Weimei, Thuring, Jan Willem, Van Hecke, Kristof, Verhoeven, Jonas, Verniest, Guido, Vos, Ann, Wu, Tongfei   +10 more
core   +1 more source

Insights into the Phytochemistry of the Cuban Endemic Medicinal Plant Phyllanthus orbicularis: Fideloside, a Novel Bioactive 8-C-glycosyl 2,3-Dihydroflavonol

Molecules, 2019
Phyllanthus orbicularis (Phyllanthaceae) is an endemic evergreen tropical plant of Cuba that grows in the western part of the island and is used in traditional medicine as an infusion.
Antonio Francioso, Katrin Franke, Claudio Villani, Luciana Mosca, Maria D’Erme, Stefan Frischbutter, Wolfgang Brandt, Angel Sanchez-Lamar, Ludger Wessjohann   +8 more
doaj   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina, Jamison, Matthew T, Molinski, Tadeusz F, Wang, Xiao   +3 more
core  

Crystal structure, computational study, and Hirshfeld analysis of exo-1,2,3,5-tetraphenyl-1a',9b'-dihydrospiro[bicyclo[3.1.0]hexane-6,1′-cyclopropa[l]phenanthren]-2-en-4-one

Acta Crystallographica Section E: Crystallographic Communications
The reaction of dibenzonorcarynyliden(e/oid) with phencyclone was recently reported to give a congested spiropentane with endo stereochemistry. Herein we report that, in sharp contrast, an analogous reaction using tetracyclone, instead of phencyclone ...
Alexander D. Roth, Dasan M. Thamattoor
doaj   +1 more source

The C–F bond as a conformational tool in organic and biological chemistry

Beilstein Journal of Organic Chemistry, 2010
Organofluorine compounds are widely used in many different applications, ranging from pharmaceuticals and agrochemicals to advanced materials and polymers.
Luke Hunter
doaj   +1 more source

Chemical Synthesis of the Lantibiotic Lacticin 481 Reveals the Importance of Lanthionine Stereochemistry

Journal of the American Chemical Society, 2013
Lantibiotics are a family of antibacterial peptide natural products characterized by the post-translational installation of the thioether-containing amino acids lanthionine and methyllanthionine.
P. Knerr, W. A. van der Donk
semanticscholar   +1 more source

An easy α-glycosylation methodology for the synthesis and stereochemistry of mycoplasma α-glycolipid antigens

Beilstein Journal of Organic Chemistry, 2012
Mycoplasma fermentans possesses unique α-glycolipid antigens (GGPL-I and GGPL-III) at the cytoplasm membrane, which carry a phosphocholine group at the sugar primary (6-OH) position.
Yoshihiro Nishida, Yuko Shingu, Yuan Mengfei, Kazuo Fukuda, Hirofumi Dohi, Sachie Matsuda, Kazuhiro Matsuda   +6 more
doaj   +1 more source

An oxorhenium complex bearing a chiral cyclohexane‐1‐olato‐2‐thiolato ligand: Synthesis, stereochemistry, and theoretical study of parity violation vibrational frequency shifts [PDF]

, 2017
Nidal Saleh, Radovan Bast, Nicolas VANTHUYNE, Christian Roussel, Trond Saue, Benoit Darquié, Jeanne Crassous, Nidal Saleh, Radovan Bast, Nicolas VANTHUYNE, Christian Roussel, Trond Saue, Benoit Darquié, Jeanne Crassous   +13 more
openalex   +1 more source

Stereochemical outcomes of C–F activation reactions of benzyl fluoride

Beilstein Journal of Organic Chemistry, 2018
In recent years, the highly polar C–F bond has been utilised in activation chemistry despite its low reactivity to traditional nucleophiles, when compared to other C–X halogen bonds.
Neil S. Keddie, Pier Alexandre Champagne, Justine Desroches, Jean-François Paquin, David O'Hagan   +4 more
doaj   +1 more source

On the Stereochemistry of Lignin Model Compounds of the 1,2-Diaryl-1,3-propanediol Type. The Crystal Structure of erythro-2-(4-Methoxyphenyl)-1-phenyl-1,3-propanediol. [PDF]

, 1987
Knut Lundquist, Rolf Stomberg, Jan Sandström, Ann‐Britt Wassgren   +3 more
openalex   +1 more source