Results 141 to 150 of about 118,878 (273)

Stereochemistry [PDF]

Nature, 1894
openaire   +1 more source

Catalytic Enantioselective Synthesis of Conformationally Stable C(sp2)−C(sp3) Naphthocoumarin Atropisomers

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
The enantioselective synthesis of naphthocoumarin adducts via a tandem organocatalytic 1,4‐addition/decarboxylation delivers excellent control over a newly forged stereocenter and yields configurationally stable synclinal atropisomers. The process features broad substrate scope and scalability, and its structural and mechanistic foundations are ...
M. Chiara Cabua, Davide Moi, Emanuele Cocco, Valentina Onnis, Enrico Podda, David J. Aitken, Armando Carlone, Renzo Luisi, Enrica Tuveri, Drew F. Parsons, Francesco Secci   +10 more
wiley   +1 more source

Asymmetric Transformations of α,β‐Unsaturated Oxazolidinones Catalyzed by C2‐Symmetric Chiral Iron Triad Complexes

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley   +1 more source

Physical Implausibility of Carbohydrate Ligands in Results of Deep Learning-Based Cofolding Methods. [PDF]

J Chem Inf Model
Luthfi M, Simpkin AJ, Elliott LG, Sompornpisut P, Rigden DJ.   +4 more
europepmc   +1 more source

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

ChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Influence of molecular shape and hydrogen bonding on glycolipid self-assembly into thermotropic gyroid phases. [PDF]

Chem Sci
Das S, Zheng C, Lodge TP, Siepmann JI, Calabrese MA, Reineke TM.   +5 more
europepmc   +1 more source

Regioselective Tele‐Substitution of Aroyl Chlorides via Activation by an Al/P Frustrated Lewis Pair

ChemistryEurope, Volume 4, Issue 5, May 2026.
A tele‐substitution of aroyl chlorides with silyl ketene acetals is enabled by an ortho‐phenylene‐linked Al/P frustrated Lewis pair. Intramolecular aluminum activation polarizes the aroylphosphonium intermediate, promoting regioselective dearomative nucleophilic addition to the aromatic ring.
Hirotaka Okamoto, Yoshihiro Nishimoto, Makoto Yasuda   +2 more
wiley   +1 more source

Remote Stereocontrol in Aryl/Alkyl C-H Insertion Reactions of Rhodium Carbenes: Assembly of Pseudorigidols A and B. [PDF]

Org Lett
Ung L, Dishman SN, Zhang S, Fettinger JC, Shaw JT.   +4 more
europepmc   +1 more source

Evaluation of Different Detection and Identification Methods of Intact Tetrahydro‐Methyltestosterone Sulfate Metabolites in Doping Control

Drug Testing and Analysis, Volume 18, Issue 5, Page 678-689, May 2026.
The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis, Olga Goula, Polyxeni Kiousi, Panagiotis Sakellariou   +3 more
wiley   +1 more source

Clinically relevant stereochemistry reprograms amyloid proteome for aggregation cross-talk-conferred neuroprotection. [PDF]

Sci Adv
Zhou J, Liu J, Liu X, Ren L, Yu Z, Zheng Z, Li G.   +6 more
europepmc   +1 more source