Results 121 to 130 of about 40,087 (250)

Stereoselective Construction of Benzo‐Fused Tetrahydropyrrole Thiazines From Saccharin

European Journal of Organic Chemistry, EarlyView.
Saccharin was used as a template to construct a series of 10a‐substituted, benzo‐fused, pyrrolo thiazinone dioxides. Thereafter, diastereo‐divergent 10‐keto reduction gave either diastereomeric alcohol in a process that did not rely on the substituent at 10a's identity.
Seanán Doyle, Matthew Kiernan, Jordan Smyth, Ajay Mathew, Conor J. Crawford, Julia Bruno‐Colmenarez, Patrick J. Guiry, Aisha Khalifa, Paul Evans   +8 more
wiley   +1 more source

Syntheses of all stereoisomers of aptosimon (9-oxosesamin) and their effects on plant growth regulation and diacylglycerol acyltransferase inhibition. [PDF]

J Pestic Sci
Okada M, Iwata A, Nishiwaki H, Mori S, Yamauchi S.   +4 more
europepmc   +1 more source

Diastereoselective Synthesis of Highly Substituted Methylene Cyclobutanes by Pd Catalysis

European Journal of Organic Chemistry, EarlyView.
A chemo‐ and diastereoselective palladium‐catalyzed intramolecular coupling/cyclization of borylated 1,5‐dienes, readily accessible by allene allylboration, with iodoarenes enables the synthesis of highly substituted methylene cyclobutanes. The method exhibits broad scope, high functional group tolerance, and complete enantiospecificity.
Jose M. Malga, Martín Fañanás‐Mastral   +1 more
wiley   +1 more source

A novel stereochemistry retention mechanism in the S_N2 reaction. [PDF]

Nat Commun
Song Z, Gao H, Xie J.
europepmc   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Remote Stereocontrol in Aryl/Alkyl C-H Insertion Reactions of Rhodium Carbenes: Assembly of Pseudorigidols A and B. [PDF]

Org Lett
Ung L, Dishman SN, Zhang S, Fettinger JC, Shaw JT.   +4 more
europepmc   +1 more source

Stereoselective and Diastereospecific Aminosilylation and Hydrosilylation of Heterobicyclic Alkenes by Copper Catalysis Under Mild Conditions

European Journal of Organic Chemistry, EarlyView.
An efficient and straightforward methodology for the stereoselective and diastereospecific aminosilylation and hydrosilylation of heterobicyclic norbornene derivatives is introduced. The mild conditions enable the functionalization of norbornene substrates with broad functional‐group tolerance.
Daniel Kamzol, Wende Chen, Aleksander Hoffman, René Wilhelm   +3 more
wiley   +1 more source

Clinically relevant stereochemistry reprograms amyloid proteome for aggregation cross-talk-conferred neuroprotection. [PDF]

Sci Adv
Zhou J, Liu J, Liu X, Ren L, Yu Z, Zheng Z, Li G.   +6 more
europepmc   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Design, synthesis, and biological evaluation of FXR/ASK1 dual-target modulators. [PDF]

Beilstein J Org Chem
Zhang X, Wang J, Zhao Z, Wang C, Ye Z, Ma WY, Xu JX, Zhang F.   +7 more
europepmc   +1 more source