Results 131 to 140 of about 63,316 (301)
Dibenzosuberene‐Winged Polycyclic Aromatic Hydrocarbons
European Journal of Organic Chemistry, EarlyView.The twisted acene 8, which features two dibenzosuberene “wings”, was prepared by the addition of a crowded aryne to a similarly “winged” cyclopentadienone. Compound 8 is chiral, and it has a high barrier to thermal racemization (ΔG‡rac = 36 kcal/mol), but it undergoes fast photochemical racemization even in ambient light.
Mingshu Xie +3 more
wiley +1 more source
Total Synthesis and Stereochemistry of the Antitumor Antibiotic PD 113,271
, 2016 Total Synthesis and Stereochemistry of the Antitumor Antibiotic PD 113 ...
Toshifumi Takeuchi (1350783) +3 more
core +1 more source
European Journal of Organic Chemistry, EarlyView.Asymmetric synthesis of antimalarial yingzhaosu C was achieved in 4–5 steps by asymmetric Grignard synthesis of (R)‐gossonorol followed by novel enantiospecific hydroperoxidation. We report a concise asymmetric synthesis of antimalarial yingzhaosu C in 59% ee.
Saranna E. Kavanagh +2 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.The regio‐ and stereoselective synthesis of ring‐fused α‐hydroxy‐2‐cyclopentenones is achieved by a one‐pot gold(I)‐catalyzed Rautenstrauch rearrangement/nitrosocarbonyl hetero‐Diels–Alder reaction/ring opening sequence carried out on suitable propargyl esters followed by selective NO bond cleavage.
Dina Scarpi +3 more
wiley +1 more source
The Stereochemistry of Dihydrolycorine.
Pharmaceutical Bulletin, 1957 Takeda, Kenichi, Kotera, Katsumi
openaire +3 more sources
Facile Method for Determining Lanthipeptide Stereochemistry
Lanthipeptides make up a large group of natural products that belong to the ribosomally synthesized and post-translationally modified peptides (RiPPs).
Autumn M. Frerk (17804999) +3 more
core +1 more source
Retention Stereochemistry of Thermal 1,3-Silyl Migration in Allylsilanes
, 2016 Retention Stereochemistry of Thermal 1,3-Silyl Migration in ...
Mitsuo Kira (1737751) +2 more
core +1 more source
Safracin B as a Synthetic Linchpin: From Natural Product to Drug Intermediate and Beyond
European Journal of Organic Chemistry, EarlyView.Safracin B is employed as a key precursor for the streamlined preparation of cyanosafracin B and safracin A. Careful tuning of the reaction parameters affords these derivatives in high efficiency, and full nuclear magnetic resonance signal assignments are established for the complex safracin frameworks.
Paolo Orlando +5 more
wiley +1 more source
Stereochemistry of the Core Structure of the Mycolactones
, 2016 Stereochemistry of the Core Structure of the ...
Andrew B. Benowitz (2984721) +3 more
core +1 more source
Total Synthesis of Sacrolide A and Cytotoxic Evaluation
European Journal of Organic Chemistry, EarlyView.Isolated from the edible cyanobacterium Aphanothece sacrum, sacrolide A is a highly potent antimicrobial and cytotoxic metabolite. Its total synthesis via a convergent strategy enabled accurate assessment of its effects on liver and colon cells, offering new insights into its bioactivity and potential health risks.
Priyanka Kataria +7 more
wiley +1 more source