Results 151 to 160 of about 40,087 (250)

Collective Asymmetric Total Syntheses of Musellarins A-E. [PDF]

J Org Chem
Liu Y, Ou Y, Chang V, Yao H, Tong R.
europepmc   +1 more source

Dose–response modelling uncovers compound‐specific inhibitory effects of host defence volatiles on mountain pine beetle fungal symbionts

Pest Management Science, EarlyView.
Host defence volatiles inhibit mountain pine beetle fungal symbionts in a compound‐ and enantiomer‐specific manner, with distinct dose–response profiles that reveal the multitarget chemical defences of beetle–fungi symbiotes. Abstract BACKGROUND The mountain pine beetle relies on symbiotic fungi to overcome host tree defences, yet these fungi must ...
Duo Zhang, Yanzhuo Liu, Xinyi Zhao, Guncha Ishangulyyeva, Nadir Erbilgin   +4 more
wiley   +1 more source

Can You Help ChatGPT Get an "A" in Organic Chemistry? Teaching Effective Prompting of Large Language Models for Reaction Prediction. [PDF]

J Chem Educ
Thrall ES, Vanden Assem OM, Schneider JA, Schrier J, Tassoti S.   +4 more
europepmc   +1 more source

Soil‐dependent variation in strigolactone signaling distance revealed by a parasitic seed germination bioassay

Pest Management Science, EarlyView.
A parasitic seed germination bioassay reveals strong soil‐dependent variation in strigolactone signaling distance, controlled by physical and biological soil properties, which shapes signaling range and parasitic weed infection risk. Abstract BACKGROUND Strigolactones are root‐exuded plant metabolites acting as germination stimulants for several ...
Hammam Ziadne, Roni Gafni, Amit Paporisch   +2 more
wiley   +1 more source

Advances in Enantioselective Synthesis and Chiral Resolution of Insecticides. [PDF]

Molecules
López-Rosas CA, Delgado-Alvarado E, Barrera-Méndez F, Bonilla-Landa I, Olivares-Romero JL.   +4 more
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Co-Translational Incorporation of <i>(R)</i>- and <i>(S)</i>-β²-Hydroxy Acids <i>In Vitro</i>: A Structural and Biochemical Study on the <i>E. coli</i> Ribosome. [PDF]

J Am Chem Soc
Majumdar C, Kent AD, Hamlish NX, Zhu C, Fitzgerald KA, Cate JHD, Schepartz A.   +6 more
europepmc   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

Enantioselective Carbonyl Crotylation of Alcohol Proelectrophiles via Ruthenium-Catalyzed Hydrogen Autotransfer: Innovation Inspired by Polyketide Total Synthesis. [PDF]

ACS Catal
Meares PW, Santana CG, Krische MJ.
europepmc   +1 more source

Creating a Masterpiece. The Road to (and Beyond) Woodward and Hoffmann's 1969 Angewandte Chemie Treatise

The Chemical Record, EarlyView.
This publication describes how R. B. Woodward and Roald Hoffmann crafted their masterpiece publications. Illustrations include Woodward's first draft of the famous “Violations There are none. Nor can violations be expected of so fundamental a principle of maximum bonding.” Original but discarded text shows the stepwise paths toward the W‐H masterpieces.
Jeffrey I. Seeman
wiley   +1 more source