Results 221 to 230 of about 138,145 (310)

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Copper-catalyzed stereospecific methoxyboration of styrenes enabled by oxygen umpolung with acetal-based peroxides. [PDF]

Chem Sci
Fujiwara K, Nakamura S, Hirano K.
europepmc   +1 more source

Absolute Stereochemistries of Sylvaticin and 12,15-cis-Sylvaticin, Bioactive C-20,23-cis Non-adjacent Bistetrahydrofuran Annonaceous Acetogenins, from Rollinia mucosa

, 1995
Jerry L. McLaughlin, Guoen Shi, Lu Zeng, Zhe-ming Gu, John M. MacDougal   +4 more
openalex   +1 more source

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

The FEBS Journal, EarlyView.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

Stereoselective Cytotoxicity of Enantiopure 3,3-Dichloro-γ-lactams: Correlating In Vitro Activity with In Vivo Tolerability. [PDF]

Molecules
Diaba F, Teixidó E, Morán MDC.
europepmc   +1 more source

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

The FEBS Journal, EarlyView.
We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink, Joshua N. Whitehead, Linus O. Johannissen, Nigel S. Scrutton   +3 more
wiley   +1 more source

Chemical Deuteration of α-Amino Acids and Optical Resolution: Overview of Research Developments. [PDF]

Bioengineering (Basel)
Yepuri NR.
europepmc   +1 more source

Stereochemistry of synringostatin, syringomycin and syringotoxin, phytotoxins of Pseudomonas syringae pv. syringae.

, 1991
Naoyuki Fukuchi, Akira Isogai, Akinori Suzuki   +2 more
openalex   +2 more sources

Drivers of strigolactone diversity: P450s in strigolactone biosynthesis

Journal of Integrative Plant Biology, EarlyView.
This review summarizes the discovery and functional identification of cytochrome P450 in strigolactone biosynthesis, classifies and summarizes the members discovered so far, clarifies their biological significance, discusses the technology of strigolactone synthesis research, and finally describes some problems in strigolactone research and potential ...
Changbin Niu, Harro J. Bouwmeester, Changsheng Li   +2 more
wiley   +1 more source

Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis. [PDF]

New Phytol
Mann SGA, Paz-Galeano M, Shahsavarani M, Perley JO, Guo J, Garza-Garcia JJO, Qu Y.   +6 more
europepmc   +1 more source