Results 221 to 230 of about 63,316 (301)

Stereodivergent Synthesis of Three Contiguous Stereogenic Centers by Cu/Ir-Catalyzed Borylallylation. [PDF]

Angew Chem Int Ed Engl
Das S, Dorn SK, Brown MK.
europepmc   +1 more source

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

Engineering Polyketide Stereocenters with Ketoreductase Domain Exchanges. [PDF]

J Am Chem Soc
Keiser LS, Gatenil PP, Zhu Y, Deng K, Waldburger L, Gin JW, Chen Y, Baidoo EEK, Petzold CJ, Lanclos N, Northen TR, Englund E, Keasling JD.   +12 more
europepmc   +1 more source

Single‐Sequence Deep Learning Delivers Crystal‐Quality Models of Covalent K‐Ras G12 Hotspot Complexes

IUBMB Life, Volume 78, Issue 6, June 2026.
ABSTRACT Structure‐based design of covalent drugs has achieved tremendous success by understanding and leveraging the three‐dimensional interactions between small‐molecule drug candidates and their protein targets. However, this approach traditionally relies on high‐resolution co‐complex structures obtained by X‐ray crystallography, NMR, or cryo‐EM ...
Sungwon Jung, Qinheng Zheng, Kevan M. Shokat   +2 more
wiley   +1 more source

Stereospecific cross-coupling reactions: Programmed assembly of chiral molecules by reaction of chiral reagents. [PDF]

Sci Adv
Liang H, Zhang X, Morken JP.
europepmc   +1 more source

Concentration and composition of condensed tannins in leaves from fodder trees and shrubs in Pakistan

JSFA reports, Volume 6, Issue 6, Page 212-219, June 2026.
Abstract Background The lack of dependable, high‐quality forage and animal feedstuffs in many areas of the world hampers livestock production. In these regions, farmers often rely on native fodder tree and shrub leaves as a forage source for their animals with little or no information available on nutritional factors of these feedstuffs.
Ishrat Roomi, Wayne E. Zeller, Matt Akins, Azhar Hussain   +3 more
wiley   +1 more source

Improving Stereochemical Limitations in Protein-Ligand Complex Structure Prediction. [PDF]

ACS Omega
Ishitani R, Moriwaki Y.
europepmc   +1 more source

Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis

ChemistryOpen, Volume 15, Issue 6, June 2026.
This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley   +1 more source

Editor's Choice JAAG: a JSON input file assembler for AlphaFold 3 with glycan integration. [PDF]

Glycobiology
Huang C, Moremen KW.
europepmc   +1 more source