The complete stereochemistry of the antibiotic candicidin A3 (syn. ascosin A3, levorin A3)
Julia Borzyszkowska-Bukowska +5 more
openalex +2 more sources
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
Dual Biological Potential: Anticancer and Antibacterial Activities of Bis-α, ω-Bifunctional Sphingolipids from the Marine Sponge Oceanapia ramsayi. [PDF]
Keneni DA +7 more
europepmc +1 more source
Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat +6 more
wiley +1 more source
By harnessing chalcogen bonding (ChB) catalysis, an exclusive access into a highly stereoselective strain‐release C‐glycosylation pathway was discovered. This was surprisingly not replicable by the conceptually similar halogen bonding (XB) catalysis.
Hao Guo, Charles C. J. Loh
wiley +2 more sources
A Plant‐Based Platform for the Production of Bark Beetle Pheromones
ABSTRACT Bark beetle species of the genera Ips and Dendroctonus represent a threat to forests in both North America and Europe. Under normal circumstances, these beetles recycle dying trees into nutrients, but under certain conditions, growing populations can overcome healthy tree defenses and cause severe economic loss in forestry.
Abraham Ontiveros‐Cisneros +7 more
wiley +1 more source
Total Synthesis and Anticancer Study of (+)-Verticillin A. [PDF]
Knauss W +4 more
europepmc +1 more source
Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim +16 more
wiley +1 more source
Advancing Structure Elucidation with a Flexible Multi‐Spectral AI Model
The MultiModalSpectralTransformer (MMST) is an automated tool that helps identify molecular structures by combining different spectroscopic methods, including 2D and 1D NMR, IR, and MS, within a unified AI framework. Trained on 4 million simulated compounds, MMST achieves 72% top‐1 accuracy in molecular identification and adapts to new chemical spaces ...
Martin Priessner +6 more
wiley +2 more sources
Stereoisomer library prepared <i>via</i> controlled radical polymerization: isolation, structural identification and discovery of stereospecific gelation behaviour of tri(N-phenyl acrylamide). [PDF]
Nagai Y +12 more
europepmc +1 more source

