Results 141 to 150 of about 15,265 (249)

Natural and Synthetic Metabolic Architectures

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Metabolism yields function through architecture, not through isolated parts. This Perspective article discusses how design can move from components to connectivity and then to architectural regimes that account for space, time, and routing. The framework links understanding to engineering and helps explain why microbial engineering meets challenges ...
Pablo I. Nikel
wiley   +1 more source

Rigorous treatment of polytopal rearrangements reveal surprising complexity of stereoisomerism configuration landscapes. [PDF]

Chem Sci
Canfield PJ, Crossley MJ.
europepmc   +1 more source

Development of Styryl‐Modified 3,4‐Dihydropyrimidin‐2(1H)‐ones as Potential Antitumor Agents

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Styryl‐modified 3,4‐dihydropyrimidin‐2(1H)‐ones (DHPMs), designed from the Eg5 inhibitor monastrol, show markedly enhanced antiproliferative activity in HeLa and MCF‐7 cancer cells. Lead compounds 16 and 17 trigger apoptosis through cell‐line‐specific pathways and downregulate c‐Myc, emerging as promising anticancer candidates.
Konstantinos Panagoulias, Woonghee Kim, Murat Ozdemir, Busra Turan, Adil Mardinoglu, Hasan Turkez, Daniela Trisciuzzi, Orazio Nicolotti, Antonio Di Stefano, Stamatia Vassiliou, Ivana Cacciatore   +10 more
wiley   +1 more source

Catalytic Autoxidation for Depolymerization of Multilayer Plastic Films

ChemSusChem, Volume 19, Issue 7, 14 April 2026.
Catalytic autoxidation using a Co/Mn/Br catalyst system depolymerizes diverse polymers in multilayer plastic films, generating oxygenated small molecules such as dicarboxylic acids. The method tolerates additives and disrupters and converts up to 48 mol% polymer carbon into soluble products, enabling chemical recycling of complex plastic waste ...
Ciaran W. Lahive, Amy A. Cuthbertson, Anna N. Walsh, Sydney E. Reiber, Hannah M. Alt, Brenna A. Black, Christopher Botello, Jason S. DesVeaux, Spencer Lask, Clarissa Lincoln, William E. Michener, Joel Miscall, Kelsey J. Ramirez, Lisa M. Stanley, Sean P. Woodworth, Shannon S. Stahl, Gregg T. Beckham   +16 more
wiley   +1 more source

Stereoisomerism in Nanohoops with Heterogeneous Biaryl Linkages of E/Z- and R/S-Geometries

ACS Central Science, 2016
Parantap Sarkar, Zhe Sun, Toshiki Tokuhira, Motoko Kotani, Sota Sato, Hiroyuki Isobe   +5 more
doaj   +1 more source

Enantioselective Synthesis, Crystal Structures, and Stereoisomerism of Substituted o,m,o,p-Tetraphenylenes. [PDF]

Org Lett
Kawai Y, Oriki T, Sato Y, Nogami J, Kamiya Y, Suzuki S, Tanaka K.   +6 more
europepmc   +1 more source

Control over stereogenic centres beyond tetracoordination. [PDF]

Chem Sci
Budeev A, Sparr C.
europepmc   +1 more source

Slow Relaxation of the Magnetization in Dysprosium-Aluminum Metallacrowns. [PDF]

ACS Omega
Chicco S, Garlatti E, Cugini F, Rheam RE, Travis JR, Hess AM, Zeller M, Solzi M, Carretta S, Zaleski CM.   +9 more
europepmc   +1 more source

Exploiting spatial isomerism to modulate the assembled phase and rheological response of compositionally identical sugar-based surfactants. [PDF]

Chem Sci
Poon JF, Cabezón A, Gulotta A, Mahmoudi N, Ulvenlund S, Garcia-Fandiño R, Sanchez-Fernandez A.   +6 more
europepmc   +1 more source

Catalytic asymmetric construction of remote P or other heteroatom (Si/S) stereogenic axially chiral scaffolds. [PDF]

Chem Sci
Liu W, Ling Z, Liu YZ, Deng WP.
europepmc   +1 more source