Results 191 to 200 of about 17,928 (220)
Antihypertensive effects of dilevalol, a stereoisomer of labetalol
Kazuki Matsunaga +2 more
openalex +1 more source
A Triple‐Catalytic, Fully Biogenic Synthesis of Cyclic Carbonates
A three‐step synthesis of cyclic carbonates from biogenic resources (fatty acids, O2, CO2) is reported. The process operates via a visible light‐mediated hydrocarbon oxidation, with an overall 100% atom‐economy, in the presence of easily accessible catalysts (porphyrin, VO(acac)2, pyridine) but without intermediate work‐up procedures.
Robin Stuhr +2 more
wiley +1 more source
Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley +1 more source
Double Lateral Flow Test System for Simultaneous Immunodetection of Enantiomeric Forms of Antibiotics: An Ofloxacin Case Study. [PDF]
Hendrickson OD +3 more
europepmc +1 more source
Stereoselective synthesis of marine antibiotic (-)-malyngolide and its stereoisomers.
Itsuo Ichimoto +3 more
openalex +2 more sources
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
Spirocyclic Diamine Scaffolds for Medicinal Chemistry
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel +3 more
wiley +1 more source
Single-molecule nanopore sensing of proline <i>cis</i>/<i>trans</i> amide isomers. [PDF]
Iesu L +5 more
europepmc +1 more source
Synthesis of Biphenanthrene Natural Products by Atroposelective Aromatic Ring‐Opening Metathesis
Aromatic ring‐opening metathesis in natural product total synthesis allows for the streamlined stereoselective preparation of atropisomeric biphenanthrenes with an enantioselectivity of >99:1 e.r. ABSTRACT With the unique ability to cleave and form an extensive range of carbon–carbon double and triple bonds, alkene and alkyne metathesis advanced to a ...
Valeriia Hutskalova, Christof Sparr
wiley +1 more source

