Results 101 to 110 of about 30,863 (282)
Regio- and stereoselective synthesis of new diaminocyclopentanols
Beilstein Journal of Organic Chemistry, 2014 The optimal conditions for regio- and stereoselective epoxide ring opening of N,N-disubstituted 1,2-epoxy-3-aminocyclopentanes by different nucleophilic reagents have been developed.
Evgeni A. Larin +2 more
doaj +1 more source
Improving the Stereoselectivity of Bakers' Yeast Reductions by Genetic Engineering
, 2016 The stereoselectivities of bakers' yeast catalyzed reductions of β-keto esters can be manipulated by genetic design. Strains in which two major β-keto ester reductases are either knocked out or overexpressed have been constructed.
Jon D. Stewart (1323831) +2 more
core +1 more source
Stereoselectivity of the interaction of muscarinic antagonists with their receptors
, 1989 The stereoselectivity of the interaction with muscarinic receptors of enantiomers of a series of chiral antagonists is receptor subtype dependent. There is no overall relationship between stereoselectivity and receptor affinity.
Christophe, Jean +8 more
core
Angewandte Chemie International Edition, EarlyView.A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang +5 more
wiley +1 more source
Tertiary alcohol preferred: Hydroxylation of trans-3-methyl-L-proline with proline hydroxylases
Beilstein Journal of Organic Chemistry, 2011 The enzymatic synthesis of tertiary alcohols by the stereospecific oxidation of tertiary alkyl centers is a most-straightforward but challenging approach, since these positions are sterically hindered.
Christian Klein, Wolfgang Hüttel
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.The straightforward conversion of alcohols to tertiary or secondary amines employing Nms‐amides in a single operation is described. The transformation features broad functional group tolerance and high stereospecificity, underscoring its utility in the synthesis of isotope‐labeled pharmaceuticals.
Jakub Brześkiewicz +3 more
wiley +1 more source
Understanding Enzyme Stereoselectivity and Substrate Specificity of Aldo-Keto Reductases
, 2015 Understanding Enzyme Stereoselectivity and Substrate Specificity of Aldo-Keto ...
Flingos, Emily +4 more
core
Clay minerals and their gallery guests: an ab initio investigation into their interactions. [PDF]
, 2011 Clay minerals are ubiquitous and readily accessible in the natural environment and consequently have become an essential ingredient in the development of Western Society.
GEATCHES, DAWN,LESLEY +1 more
core
Formation of Highly Selective Binding Pockets in UiO‐Type MOFs From Bridged Linkers
Angewandte Chemie International Edition, EarlyView.Much room for design: We present a generalizable strategy for precisely modifying UiO‐type Metal‐organic frameworks with functional groups in a site‐specific manner. Through the use of pre‐connected linkers, pocket‐like pores for molecular recognition are generated.
Tobias Hennig +7 more
wiley +1 more source
Molecular Basis for the Substrate Stereoselectivity in Tryptophan Dioxygenase
, 2016 Tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are the only two heme proteins that catalyze the oxidation reaction of tryptophan (Trp) to N-formylkynurenine.
Dario A. Estrin (120783) +4 more
core +1 more source