Results 91 to 100 of about 27,319 (289)
Synthetic explorations of the briarane jungle: progress in developing a synthetic route to a common family of diterpenoid natural products [PDF]
Royal Society Open Science, 2018 The briarane diterpenoids are a large family of marine natural products that have been primarily isolated from gorgonian octocorals around the world.
Nicholas G. Moon, Andrew M. Harned
doaj +1 more source
Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration
Angewandte Chemie, EarlyView.The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti +9 more
wiley +2 more sources
Biomolecules, 2020 Fluostatins, benzofluorene-containing aromatic polyketides in the atypical angucycline family, conjugate into dimeric and even trimeric compounds in the post-biosynthesis.
Yuanqi Wang +4 more
doaj +1 more source
Origins of Stereoselectivity in the α-Alkylation of Chiral Hydrazones
, 2016 Density functional theory calculations and experiment reveal the origin of stereoselectivity in the deprotonation−alkylation of chiral N-amino cyclic carbamate (ACC) hydrazones. When the ACC is a rigid, camphor-derived carbamate, the two conformations of
Sarah E. Wengryniuk (1991857) +4 more
core +3 more sources
A stereoselective synthesis of (−)-tetrahydrolipstatin [PDF]
Chemical Communications, 1999 A stereoselective synthesis of (–)-tetrahydrolipstatin has been accomplished utilizing olefin metathesis of an acrylate ester as the key step.
Arun K, Ghosh, Chunfeng, Liu
openaire +2 more sources
Angewandte Chemie, EarlyView.Methyl substitution positions on the nylon‐6 backbone markedly affect crystallizability, thermomechanical properties, and recyclability of the resulting atactic nylon‐6 variants. While γ‐methyl substitution gives an amorphous nylon, all other four methyl‐substitution positions (α, β, δ, and ε) afford, unexpectedly, crystalline nylons, showing tacticity‐
Jun‐Jie Tian +9 more
wiley +2 more sources
Synthetic avenues towards a tetrasaccharide related to Streptococcus pneumonia of serotype 6A
Beilstein Journal of Organic Chemistry, 2018 Streptococcus pneumonia (SPn) is a Gram-positive bacterium which causes life threatening diseases. The bacteria protect themselves against non-specific host defence by an external polysaccharide (PS) capsule which bears a repeating unit, α-D-Galp(1->3)-α-
Aritra Chaudhury +2 more
doaj +1 more source
How O-Substitution of Sialyl Donors Affects Their Stereoselectivity
, 2016 The profound effect of substituents at C-5 of glycosyl sialosides on their stereoselectivity is well-known although the exact nature of this effect is somewhat less understood.
Cristina De Meo (1535950) +5 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2012 We have designed a new sequential carbocupration and sulfur–lithium exchange that leads stereo- and regioselectively to trisubstituted alkenyllithiums.
Andreas Unsinn, Cora Dunst, Paul Knochel
doaj +1 more source
N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis
Beilstein Journal of Organic Chemistry, 2012 The interplay between metals and N-heterocyclic carbenes (NHCs) has provided a window of opportunities for the development of novel catalytic strategies within the past few years.
Rob De Vreese, Matthias D’hooghe
doaj +1 more source