Results 111 to 120 of about 30,863 (282)
Stereoselectivity in Glycosylation with Deoxofluorinated Glucosazide and Galactosazide Thiodonors
, 2019 Control of anomeric stereoselectivity in glycosylation with deoxofluorinated glycosyl donors is critical for assembly of fluorinated oligosaccharides. Here, we report the synthesis of benzylated 3-fluoro and 4-fluoro analogues of phenyl 1-thioglucosazide
Monika Müllerová (6671789) +13 more
core +1 more source
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Angewandte Chemie International Edition, EarlyView.Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Origin of the Relative Stereoselectivity of the β-Lactam Formation in the Staudinger Reaction
, 2016 The relative (cis, trans) stereoselectivity of the β-lactam formation is one of the critical issues in the Staudinger reaction. Although many attempts have been made to explain and to predict the stereochemical outcomes, the origin of the ...
Lei Jiao (780172) +2 more
core +1 more source
Stereoselectivity in DNA-Templated Organic Synthesis and Its Origins
, 2016 DNA-templated synthesis is a surprisingly general strategy for controlling chemical reactivity that enables synthetic products to be manipulated in ways previously available only to biological macromolecules.
David R. Liu (220122) +1 more
core +1 more source
Enzyme Stereoselectivity and Substrate Specificity of Yeast Reductase YDL124w
, 2014 Enzyme Stereoselectivity and Substrate Specificity of Yeast Reductase ...
Rivas-Torres, Esmeralda
core
Enzyme Stereoselectivity and Substrate Specificity of Aldo-KetoReductases
, 2015 Enzyme Stereoselectivity and Substrate Specificity of Aldo ...
Flingos, Emily +4 more
core
Biotechnology and Bioengineering, EarlyView.A recombinant whole‐cell platform expressing a bacterial 15S‐LOX exhibiting 5S‐LOX activity enabled the stereoselective production of RvE2 and 17R‐RvD5 from 18R‐HEPE and 17R‐HDHA, achieving final concentrations of 0.57 mM and 1.48 mM from 4.0 mM substrates, respectively, under optimized conditions.
Hee‐Gyeong Lee +2 more
wiley +1 more source
Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations
Chemistry – A European Journal, EarlyView.The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern +4 more
wiley +1 more source
FLP Mediated Conversion of Difluorobenzylalkynes to Fluoroallenyl Oniums via an SN1’ Pathway
Chemistry – A European Journal, EarlyView.Frustrated Lewis pair (FLP) selective C‒F activation of difluorobenzylalkynes allows the formation of fluoroallenic oniums via an SN1’ substitution pathway. The fluoroallenic onium salts are synthetic precursors that allow subsequent functionalization at allenic and onium positions.
Max Coles +6 more
wiley +1 more source
Recent advances in allylation of chiral secondary alkylcopper species
Beilstein Journal of Organic ChemistryThe transition-metal-catalyzed asymmetric allylic substitution represents a pivotal methodology in organic synthesis, providing remarkable versatility for complex molecule construction.
Minjae Kim +4 more
doaj +1 more source