Results 111 to 120 of about 27,319 (289)
Improving the Stereoselectivity of Bakers' Yeast Reductions by Genetic Engineering
, 2016 The stereoselectivities of bakers' yeast catalyzed reductions of β-keto esters can be manipulated by genetic design. Strains in which two major β-keto ester reductases are either knocked out or overexpressed have been constructed.
Jon D. Stewart (1323831) +2 more
core +1 more source
Regio- and stereoselective synthesis of new diaminocyclopentanols
Beilstein Journal of Organic Chemistry, 2014 The optimal conditions for regio- and stereoselective epoxide ring opening of N,N-disubstituted 1,2-epoxy-3-aminocyclopentanes by different nucleophilic reagents have been developed.
Evgeni A. Larin +2 more
doaj +1 more source
, 2018 Ketoreductase enzymes (KRs) with a high degree of regio- and stereoselectivity are useful biocatalysts for the production of small, specific chiral alcohols from achiral ketones.
Marc, van der Kamp +1 more
core +1 more source
Sulfur‐Directed Construction of Vinyl Cyclopropanes from 1,3‐Dienes
Angewandte Chemie International Edition, EarlyView.Sulfur takes control. A pending thioether acts as a molecular compass, directing carbene addition to the 1,3‐diene scaffold with exceptional regio‑ and diastereocontrol to forge sulfur‐substituted vinyl cyclopropanes (S‐VCPs) — molecular architectures inaccessible via conventional cyclopropanation strategies.
Anna Keimer +6 more
wiley +1 more source
Stereoselectivity of the interaction of muscarinic antagonists with their receptors
, 1989 The stereoselectivity of the interaction with muscarinic receptors of enantiomers of a series of chiral antagonists is receptor subtype dependent. There is no overall relationship between stereoselectivity and receptor affinity.
Christophe, Jean +8 more
core
Tertiary alcohol preferred: Hydroxylation of trans-3-methyl-L-proline with proline hydroxylases
Beilstein Journal of Organic Chemistry, 2011 The enzymatic synthesis of tertiary alcohols by the stereospecific oxidation of tertiary alkyl centers is a most-straightforward but challenging approach, since these positions are sterically hindered.
Christian Klein, Wolfgang Hüttel
doaj +1 more source
Stereoselectivity in Glycosylation with Deoxofluorinated Glucosazide and Galactosazide Thiodonors
, 2019 Control of anomeric stereoselectivity in glycosylation with deoxofluorinated glycosyl donors is critical for assembly of fluorinated oligosaccharides. Here, we report the synthesis of benzylated 3-fluoro and 4-fluoro analogues of phenyl 1-thioglucosazide
Monika Müllerová (6671789) +13 more
core +1 more source
Molecular Basis for the Substrate Stereoselectivity in Tryptophan Dioxygenase
, 2016 Tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are the only two heme proteins that catalyze the oxidation reaction of tryptophan (Trp) to N-formylkynurenine.
Dario A. Estrin (120783) +4 more
core +1 more source
, 2007 Radical synthesis of biaryls and dihydrobiaryls: Controlling stereoselectivity in ...
Miteshkumar. Patel (7977485)
core
Origin of the Relative Stereoselectivity of the β-Lactam Formation in the Staudinger Reaction
, 2016 The relative (cis, trans) stereoselectivity of the β-lactam formation is one of the critical issues in the Staudinger reaction. Although many attempts have been made to explain and to predict the stereochemical outcomes, the origin of the ...
Lei Jiao (780172) +2 more
core +1 more source