Results 141 to 150 of about 14,256 (222)

Bulky alkali metal cations enabled highly efficient iridium-catalyzed asymmetric hydrogenation for C-N axial chirality via dynamic kinetic resolution. [PDF]

Chem Sci
Zhao X, Chen X, Fan L, Jiang Y, Chen Y, Song D, Ling F, Hu J, Zhong W.   +8 more
europepmc   +1 more source

Diselenide‐Catalyzed Asymmetric Allenylation of Alkynes

European Journal of Organic Chemistry, Volume 29, Issue 11, 16 March 2026.
An asymmetric allenylation of alkynes is described using chiral lactamides‐based diselenides under oxidative conditions. This led to the corresponding allenylamides with enantiomeric excesses up to 72%, and uncovers an interesting stereodivergency feature related to the β‐H‐syn‐elimination of transient Se(IV) intermediates.
Rongyu Sun, Emilie Viaud, Murielle Berlande, Stéphane Quideau, Patrick Y. Toullec, Philippe A. Peixoto   +5 more
wiley   +1 more source

Stereospecific Assembly of Triply Chiral Pseudopeptidic Cages Through Dynamic Dual Chirality Transfer

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
The spontaneous assembly of triply chiral (L, Δ, P or D, Λ, M) cages has been achieved from a simple tripodal chiral effector based on phenylalanine tris(amidoamine), non‐chiral bipyridine dialdehyde, and a metal ion. Orthogonal imine bond and iron (II) coordination generate a single combination of chiral elements, while configurationally stable ...
Tushar D. Bhosale, Eudald Usan, Delia Miguel, Jordi Solà, Angel Orte, Ciril Jimeno, Ignacio Alfonso   +6 more
wiley   +2 more sources

Hexafluoroisopropanol-Promoted Stereospecific Glycosylation Enables Efficient Access to N-O-Linked 1,2-<i>cis</i>-2-Amino Glycosides. [PDF]

JACS Au
Cheng Y, Su R, Tao X, Xue XS, Dai Y.
europepmc   +1 more source

Structural and Functional Validation of Pseudomonas Savastanoi Ethylene Forming Enzymes Reveals Flexibility in 2‐Oxoglutarate Binding Mode and Conformation

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
Studies with naturally occuring variants of the Pseudomonas savastanoi ethylene‐forming enzyme (PsEFE) inform on the effect of residues on turnover and product ratio. Crystallographic studies imply a potential for metal ion sensing. Pseudomonas savastanoi pv.
Yihong Sun, Siddhant Dhingra, Mark D. Allen, Ethan S. Z. Cheng, Zhihong Zhang, Christopher J. Schofield, Lennart Brewitz   +6 more
wiley   +1 more source

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio, René Slot Bitsch, Karl Anker Jørgensen   +2 more
wiley   +2 more sources

DFT Insights into NHC-Catalyzed Switchable [3+4] and [3+2] Annulations of Isatin-Derived Enals and N-Sulfonyl Ketimines: Mechanism, Regio- and Stereoselectivity. [PDF]

Molecules
Yu S, Zhou W, Jiang Y, Wang H, Zhou X, Yang S.   +5 more
europepmc   +1 more source

Combination of a UPO‐Based Epoxidation With a Subsequent Ring‐Opening Reaction for the Synthesis of Amino Alcohols

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
The synthesis of aromatic amino alcohols via a combination of an unspecific peroxygenase‐catalysed reaction, oxyfunctionalization, and addition of selected nucleophiles and electrophiles in a highly atom‐efficient manner was investigated. This study presents the design to aim for an atom‐efficient chemo‐enzymatic synthesis route towards aromatic amino ...
Simon Last, Niklas Dietz, Martin J. Weissenborn, Jan von Langermann   +3 more
wiley   +1 more source

Understanding and Enhancing Stereoselective Polymerization Using a Data Science Approach. [PDF]

J Am Chem Soc
Kozuszek CT, Sorensen CC, Leibfarth FA.
europepmc   +1 more source

Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
The topoisomerase I inhibition and antiproliferative activities of phosphorated indenoquinoline derivatives were investigated. The target hybrid quinoline and tetrahydroquinoline compounds were synthesized via a two‐step Povarov‐type cycloaddition.
Alba Rodriguez, Elena Formoso, Birgitta R. Knudsen, Cinzia Tesauro, Maria Fuertes, Concepcion Alonso   +5 more
wiley   +1 more source