Results 221 to 230 of about 166,370 (359)

Bulky alkali metal cations enabled highly efficient iridium-catalyzed asymmetric hydrogenation for C-N axial chirality via dynamic kinetic resolution. [PDF]

Chem Sci
Zhao X, Chen X, Fan L, Jiang Y, Chen Y, Song D, Ling F, Hu J, Zhong W.   +8 more
europepmc   +1 more source

Enantioselective Determination of Chiral Fungicides in Food Samples Using Automated Dispersive Microextraction Coupled With UHPLC–MS/MS

Food Frontiers, Volume 7, Issue 2, March 2026.
The use of fatty acids and bio‐derived solvents eliminates the need for toxic solvents and, when combined with automated workstations, enables parallel sample processing, thereby improving extraction efficiency and reducing human error. ABSTRACT An enantioselective analytical method based on automated dispersive liquid–liquid microextraction (DLLME ...
Yuxin Wang, Yulin Wang, Yuanjun Nie, Jizhen Fu, Yukun Yang, Li Li, Xu Jing   +6 more
wiley   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Understanding and Enhancing Stereoselective Polymerization Using a Data Science Approach. [PDF]

J Am Chem Soc
Kozuszek CT, Sorensen CC, Leibfarth FA.
europepmc   +1 more source

Chiral N-acyliminium ions as new tools in the asymmetric synthesis of CNS-active compounds [PDF]

, 1994
Beutler, Comins, Gray, Hellmann, Irie, K.Th. Wanner, Kiguchi, Wanner, Wanner, Wong   +9 more
core   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Nonheme Fe enzyme isopenicillin N synthase was reprogrammed and evolved as an efficient nitrogen migratase IPNSNim, converting diverse azanyl esters to valuable l‐arylglycines with up to 16 000 TTN and 97:3 e.r. IPNSNim and ACCONim allowed enantiodivergent preparation of both l‐ and d‐arylglycines.
Ken Lin, Liu‐Peng Zhao, Shengchun Wang, Huichong Liu, Yu Zhang, Binh Khanh Mai, Peng Liu, Yang Yang   +7 more
wiley   +2 more sources

Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis

, 2016
Godwin A. Aleku, H. Man, Friedemann Leipold, Shahed Hussain, Laura Toca-Gonzalez, Rebecca Marchington, S. Hart, J. Turkenburg, G. Grogan, N. Turner   +9 more
semanticscholar   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Stereodivergent access to α- and β-azanucleosides <i>via</i> catalyst-free, achiral modulator-controlled iodocyclization: a concise synthesis of forodesine. [PDF]

Chem Sci
Zhong Y, Zeng J, Li M, Liang Y, Guan S, Zhao K, Mu J, Tang P, Wang H, Chen F.   +9 more
europepmc   +1 more source