Results 141 to 150 of about 147,337 (257)

Phenyl Ring: A Steric Hindrance or a Source of Different Hydrogen Bonding Patterns in Self-Organizing Systems? [PDF]

J Phys Chem Lett, 2021
Nowok A, Dulski M, Grelska J, Szeremeta AZ, Jurkiewicz K, Grzybowska K, Musiał M, Pawlus S.   +7 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Dual-targeting and steric hindrance resolution in HER2 IHC: a novel approach to improve diagnostic sensitivity. [PDF]

BMC Cancer
Luo L, Zhang X, Chen L, Chen Z, Wang Y, Huang K, Lin X, Zhu H, Du W.   +8 more
europepmc   +1 more source

Carboxylate Adsorption on Rutile TiO₂(100): Role of Coulomb Repulsion, Relaxation, and Steric Hindrance. [PDF]

J Phys Chem C Nanomater Interfaces, 2021
Nadeem IM, Hargreaves L, Harrison GT, Idriss H, Shluger AL, Thornton G.   +5 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance. [PDF]

JCI Insight
Gilchuk IM, Dong J, Irving RP, Buchman CD, Armstrong E, Turner HL, Li S, Ward AB, Carnahan RH, Crowe JE.   +9 more
europepmc   +1 more source

Investigating the Effect of Steric Hindrance within CdS Single-Source Precursors on the Material Properties of AACVD and Spin-Coat-Deposited CdS Thin Films. [PDF]

Inorg Chem, 2022
Buckingham MA, Norton K, McNaughter PD, Whitehead G, Vitorica-Yrezabal I, Alam F, Laws K, Lewis DJ.   +7 more
europepmc   +1 more source

A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems

Advanced Science, EarlyView.
Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li, Corin T. Scott, Taku Suzuki‐Osborne, John P. Lowe, Dominic Taylor, Mariolino Carta, Neil B. McKeown, Andrew D. Burrows, Lucia H. Mascaro, Frank Marken   +9 more
wiley   +1 more source

Potyviruses recruit host eIF4A3 to block m6A-mediated RNA decay by steric hindrance of viral RNA methylation in plants. [PDF]

Nucleic Acids Res
Peng D, Dong L, Wang P, Zang L, Xie J, Wang H, Li X, Fan Z, Zhou T, Du K.   +9 more
europepmc   +1 more source

London Dispersion Interactions Rather than Steric Hindrance Determine the Enantioselectivity of the Corey-Bakshi-Shibata Reduction. [PDF]

Angew Chem Int Ed Engl, 2021
Eschmann C, Song L, Schreiner PR.
europepmc   +1 more source