A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano +14 more
wiley +1 more source
Branch-Chain-Rich Diisopropyl Ether with Steric Hindrance Facilitates Stable Cycling of Lithium Batteries at - 20 °C. [PDF]
Li H +8 more
europepmc +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Steric hindrance modulated efficient thermally activated delayed fluorescence with non-linear optical, ferroelectric and piezoelectric properties. [PDF]
Dutta M +8 more
europepmc +1 more source
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang +7 more
wiley +1 more source
Regio- and Enantioselective Asymmetric Transfer Hydrogenation of One Carbonyl Group in a Diketone through Steric Hindrance. [PDF]
Khamis N +5 more
europepmc +1 more source
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
Monodisperse spherical Ag<sup>+</sup> doped Cs<sub>2</sub>KBiCl<sub>6</sub> nanocrystals: utilizing steric hindrance engineering for inkjet printing of anti-counterfeiting patterns. [PDF]
Song S +6 more
europepmc +1 more source
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang +13 more
wiley +1 more source
Steric hindrance modulation of hexaazatribenzanthraquinone isomers for high-capacity and wide-temperature-range aqueous proton battery. [PDF]
Yang M +16 more
europepmc +1 more source

