Results 101 to 110 of about 392,444 (293)
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
Steroid hormones and bone [PDF]
, 2011 Steroid hormones have an important impact on bone. The mechanism of steroid action on bone cells is through an interaction with specific receptor proteins in the target cells.
Huang, W. H., Zheng, M. H.
core +2 more sources
Advanced Science, EarlyView.In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang +20 more
wiley +1 more source
Urinary sex steroid and glucocorticoid hormones are associated with muscle mass and strength in healthy adults [PDF]
, 2019 Context Sex steroid hormones exhibit anabolic effects whereas a deficiency engenders sarcopenia. Moreover, supra-physiological levels of glucocorticoids promote skeletal muscle atrophy, while physiologic levels of glucocorticoids may improve muscle ...
Escher, Geneviève +5 more
core +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Hormone Receptors in Cervicovaginal Cells
Gynecology Obstetrics & Reproductive Medicine, 2013 Some parts of the female reproductive system such as vagina and ectocervix is covered with stratified squamous epithelium (SSE). SSE consists of many layers and steroid hormones are essential for its normal growth and development.
Şayeste Demirezen +2 more
doaj
An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS). [PDF]
The crucial role of steroid hormones in health and diseases merits their high-throughput, accurate and affordable measurements in biological specimens. Despite advances in analytical methods, sensing and quantifying steroid hormones remains challenging ...
Cretu, Victoria +10 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun +7 more
wiley +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
The profile of steroid hormones in human fetal and adult ovaries
Reproductive Biology and EndocrinologyBackground Reproduction in women is at risk due to exposure to chemicals that can disrupt the endocrine system during different windows of sensitivity throughout life.
Paraskevi Vazakidou +12 more
doaj +1 more source