Results 11 to 20 of about 59,068 (232)
Cells, 2023 DEHP is an endocrine disruptor that interferes with the function of the female reproductive system. Several studies suggested that DEHP affects steroidogenesis in human and rodent granulosa cells (GC).
Biljana Tesic +7 more
doaj +1 more source
The role of proteins implicated in skin steroidogenesis in acne vulgaris development [PDF]
Vestnik Dermatologii i Venerologii, 2023 Background. Acne vulgaris belongs to androgen-dependent diseases where androgens cause sebaceous gland hypertrophy with a subsequent enlargement of sebum production. Aims.
Andrey K. Kirichenko +5 more
doaj +1 more source
Hormones and Signaling Pathways Involved in the Stimulation of Leydig Cell Steroidogenesis
Endocrines, 2023 Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health.
Karine de Mattos +2 more
doaj +1 more source
Scientific Reports, 2021 Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig cells.
Chien Huang +7 more
doaj +1 more source
Prohibitin-1 plays a regulatory role in Leydig cell steroidogenesis
iScience, 2022 Summary: Mitochondria are essential for steroidogenesis. In steroidogenic cells, the initiation of steroidogenesis from cholesterol occurs on the matrix side of the inner mitochondrial membrane by the enzyme P450scc. This requires cholesterol import from
Geetika Bassi, Suresh Mishra
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Triclosan (TCS) is an endocrine-disrupting chemical (EDC), which is used ubiquitously as an antimicrobial ingredient in healthcare products and causes contamination in the environment such as air, water, and biosolid-amended soil.
Yatao Du +8 more
doaj +1 more source
Intestinal steroidogenesis [PDF]
Steroids, 2015 Steroids are fundamental hormones that control a wide variety of physiological processes such as metabolism, immune functions, and sexual characteristics. Historically, steroid synthesis was considered a function restricted to the adrenals and the gonads.
Bouguen, Guillaume +4 more
openaire +4 more sources
The Expanding Role of Mitochondria, Autophagy and Lipophagy in Steroidogenesis
Cells, 2021 The fundamental framework of steroidogenesis is similar across steroidogenic cells, especially in initial mitochondrial steps. For instance, the START domain containing protein-mediated cholesterol transport to the mitochondria, and its conversion to ...
Geetika Bassi +2 more
doaj +1 more source
Defects of steroidogenesis [PDF]
Journal of Endocrinological Investigation, 2010 In the biosynthesis of steroid hormones the neutral lipid cholesterol, a normal constituent of lipid bilayers is transformed via a series of hydroxylation, oxidation, and reduction steps into a vast array of biologically active compounds: mineralocorticoids, glucocorticoids, and sex hormones.
BIASON LAUBER A +3 more
openaire +4 more sources
Ecotoxicology and Environmental Safety, 2022 Fluorene-9-bisphenol (BHPF), which has been used as a substitute for bisphenol A (BPA) in consumer goods and industrial products, can be detected in environmental media and human urine. BHPF has been reported to have endocrine-disrupting effects, whereas
Yuan Huang +7 more
doaj +1 more source