Results 51 to 60 of about 59,068 (232)

Form of Supplemental Selenium Affects the Expression of mRNA Transcripts Encoding Selenoproteins, and Proteins Regulating Cholesterol Uptake, in the Corpus Luteum of Grazing Beef Cows

Animals, 2022
Selenium (Se)-deficient soils necessitate supplementation of this mineral to the diet of forage-grazing cattle. Functionally, Se is incorporated into selenoproteins, some of which function as important antioxidants.
Sarah N. Carr, Benjamin R. Crites, Joy L. Pate, Camilla H. K. Hughes, James C. Matthews, Phillip J. Bridges   +5 more
doaj   +1 more source

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica, Jonak, Carrie R, Kauffman, Alexander S, Xie, Changchuan   +3 more
core   +1 more source

Hedgehog Signaling and Steroidogenesis [PDF]

Annual Review of Physiology, 2015
Since its discovery nearly 30 years ago, the Hedgehog (Hh) signaling pathway has been shown to be pivotal in many developmental and pathophysiological processes in several steroidogenic tissues, including the testis, ovary, adrenal cortex, and placenta.
Isabella, Finco, Christopher R, LaPensee, Kenneth T, Krill, Gary D, Hammer   +3 more
openaire   +2 more sources

Cushing’s disease: adrenal steroidogenesis inhibitors

Pituitary, 2022
AbstractCushing’s disease (CD), caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor, is the most common form of Cushing’s syndrome (CS), accounting for approximately 70% of cases. CD requires a prompt diagnosis, an adequate treatment selection, and long-term management to limit hypercortisolism duration and long-term complications
Pivonello, Rosario, Simeoli, Chiara, Di Paola, Nicola, Colao, Annamaria   +3 more
openaire   +3 more sources

Determining the timeline of gonadal and genital differentiation in male and female equine fetuses allows for early detection and intervention in malformations

The Anatomical Record, EarlyView.
Abstract Sexual differentiation in the equine fetus involves coordinated morphogenetic processes that shape both the gonads and the genital ducts. Although the formation of testes and ovaries has been relatively well documented, the temporal dynamics and morphometric patterns of the mesonephric (Wolffian) and paramesonephric (Müllerian) ducts remain ...
Tais Harumi de Castro Sasahara, Silvio Pires Gomes, Fabio Cesar Magioli Abdala, Bruno Cesar Schimming, Maria Angelica Miglino   +4 more
wiley   +1 more source

Perturbing local steroidogenesis to improve breast cancer immunity

Nature Communications
Breast cancer, particularly triple-negative breast cancer (TNBC), evades the body’s immune defences, in part by cultivating an immunosuppressive tumour microenvironment.
Qiuchen Zhao, Jhuma Pramanik, Yongjin Lu, Natalie Z. M. Homer, Charlotte J. Imianowski, Baojie Zhang, Muhammad Iqbal, Sanu Korumadathil Shaji, Andrew Conway Morris, Rahul Roychoudhuri, Klaus Okkenhaug, Pengfei Qiu, Bidesh Mahata   +12 more
doaj   +1 more source

Adaptive and Biological Responses of Buffalo Granulosa Cells Exposed to Heat Stress under In Vitro Condition

Animals, 2021
The steroidogenesis capacity and adaptive response of follicular granulosa cells (GCs) to heat stress were assessed together with the underlying regulating molecular mechanisms in Egyptian buffalo.
Marwa S. Faheem, Nasser Ghanem, Ahmed Gad, Radek Procházka, Sherif M. Dessouki   +4 more
doaj   +1 more source

Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]

, 1988
We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Allolio, B., Jaursch-Hancke, C., Kaulen, D., Reincke, Martin, Schulte, H. M., Winkelmann, W.   +5 more
core   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Interlinkage between inflammation, oxidative stress, and endoplasmic reticulum stress in bisphenols-induced testicular steroidogenesis disturbance: A mini review

International Journal of Reproductive BioMedicine
Bisphenols (BP) are endocrine-disrupting chemicals that cause adverse health effects, including testicular steroidogenesis disturbance. Cyclo-oxygenase-2 and nuclear factor erythroid 2-related factor 2 are the target molecules involved in testicular ...
Nur Erysha Sabrina Jefferi, Asma Afifah Shamhari, Zariyantey Abd Hamid, Siti Balkis Budin, Izatus Shima Taib   +4 more
doaj   +1 more source