Results 211 to 220 of about 63,568 (310)

The transport of protein aggregates to the vacuole suggests a role for lipid droplets in waste disposal in Saccharomyces cerevisiae

The FEBS Journal, EarlyView.
Lipid droplets (LD) act as cellular ‘garbage trucks’ that transport cytosolic protein aggregates to the vacuole for degradation in yeast. Protein aggregates are docked to lipid droplets in a triacylglycerol‐dependent manner, transported through the cytoplasm, and transferred to the insoluble protein deposit (IPOD) at the vacuole.
Christoph Reiter, Patrick Ebner, Elli Leona Kronsteiner, Sophia Moustakakis, Markus Wiederstein, Astrid Obermayer, Ronald Thomas Huber, Christian Schloegelhofer, Florian Wieser, Jon Cedrick Richter, Isabelle Guirsch, Patrick Rockenfeller, Jana Vojtová, Tomáš Groušl, Thomas Klaus Felder, Mark Rinnerthaler   +15 more
wiley   +1 more source

Physiological Functions of Side-Chain-Retaining Sterols in the Brain and Their Roles in Neurodegenerative Diseases. [PDF]

Metabolites
Kiriyama Y, Nakatsuma A, Tokumaru H, Sadamoto H, Nochi H.   +4 more
europepmc   +1 more source

High‐Fat Diet Reprograms the Periapical Immune Landscape in a Mouse Model of Apical Periodontitis: A Spatial Transcriptomics Study

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari, Aiman Ali, Clement Hartadi, Annie Shrestha   +3 more
wiley   +1 more source

Pleiotropic Cholesterol Signaling in <i>Drosophila</i> and Mammalian Systems. [PDF]

Metabolites
Kang Y, Atif M, Lee Y.
europepmc   +1 more source

Associations between diet quality and adult acne: A cross sectional study in the UK Biobank

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Mediterranean‐style diet adherence was associated with lower odds of adult acne, particularly in women. In men, a low‐carbohydrate, high‐meat dietary pattern showed higher odds. Cooked vegetables and yoghurt were inversely associated, whereas pork, skimmed milk and milk‐based desserts showed positive associations.
Bochen Li, Yifan Xu, Ruotong Zhang, Alex Dregan, Rachel Gibson, Thivi Maruthappu, Christopher E. M. Griffiths, Wendy L. Hall   +7 more
wiley   +1 more source

Characterization and Comparison of Commercial Pumpkin (<i>Cucurbita moschata</i>) Seed Oils from Various Brands in China. [PDF]

Foods
Gao Y, Duan X, Chen Z, Zhou L, He D, Lei F.   +5 more
europepmc   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Characterization of Anti-Inflammatory and Anti-Proliferative Triterpenoids and Phytosterols from Cranberry Pomace. [PDF]

Molecules
Mia MS, Li H, Chen Y, Ferreira T, Siraj MA, Faruque M, Ma H, Khoo C, Christman L, Neto C.   +9 more
europepmc   +1 more source

Larval Arctic cod (Boreogadus saida) exhibit stronger developmental and physiological responses to temperature than to elevated pCO2

Journal of Fish Biology, EarlyView.
Abstract High‐latitude ecosystems are simultaneously warming and acidifying under ongoing climate change. Arctic cod (Boreogadus saida) are a key species in the Arctic Ocean and have demonstrated sensitivity to ocean warming and acidification as adults and embryos, but their larval sensitivity to the combined stressors is unknown. In a laboratory multi‐
Emily Slesinger, Louise A. Copeman, Benjamin J. Laurel, Mary Beth R. Hicks, Paul J. Iseri, Michelle A. Stowell, Thomas P. Hurst   +6 more
wiley   +1 more source

Phytosterol Profiling as a Tool for Edible Oil Authentication: Challenges and Prospects. [PDF]

Foods
Cheng K, Zhou T, Wang W, Zhang J, Zhou X, Hu B, Zhang T.   +6 more
europepmc   +1 more source