Results 1 to 10 of about 248 (67)
Reduced Dehydroepiandrosterone-Sulfate Levels in the Mid-Luteal Subphase of the Menstrual Cycle: Implications to Women’s Health Research [PDF]
Metabolites, 2022 The regulation of DHEA-sulfate by steroid sulfotransferase (SULT) and steryl-sulfatase (STS) enzymes is a vital process for the downstream formation of many steroid hormones. DHEA-sulfate is the most abundant steroid hormone in the human body; thus, DHEA-
Ajna Hamidovic, John Davis
exaly +4 more sources
Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics [PDF]
Drug Metabolism and Disposition, 2023 Bhagwat Prasad
exaly +2 more sources
New frontiers on the molecular underpinnings of hypospadias according to severity [PDF]
Arab Journal of Urology Arab Association of Urology, 2020 Horacio Serrano, Juan Carlos Jorge
exaly +2 more sources
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Objective. Salvianolic acid A, a natural polyphenolic ingredient extracted from traditional Chinese medicine, possesses an excellent pharmacological activity against cardiovascular diseases. Herein, therapeutic mechanisms of salvianolic acid A in myocardial infarction were explored through systematic and comprehensive network pharmacology analyses ...
Qing Huang +5 more
wiley +1 more source
Long‐lasting effects of chronic exposure to chemical pollution on the hologenome of the Manila clam
Evolutionary Applications, Volume 14, Issue 12, Page 2864-2880, December 2021., 2021 Abstract Chronic exposure to pollutants affects natural populations, creating specific molecular and biochemical signatures. In the present study, we tested the hypothesis that chronic exposure to pollutants might have substantial effects on the Manila clam hologenome long after removal from contaminated sites.
Mariangela Iannello +23 more
wiley +1 more source
Systematic Elucidation of the Mechanism of Oroxylum indicum via Network Pharmacology
Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020 Oroxylum indicum (O. indicum) is an important traditional Chinese medicine that exerts a wide spectrum of pharmacological activities. However, the pharmacological effect of O. indicum and its mechanism of action have not to be systematically elucidated yet. In this study, the druggability for active compounds of O.
Junmin Chen +3 more
wiley +1 more source
Stem Cells International, Volume 2019, Issue 1, 2019., 2019 Adipose‐derived mesenchymal stem cells (MSC‐ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC‐AT protein expression has been unclear. In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC‐MS/MS) using mouse primary ...
Yoshiki Nakashima +9 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019 Lung cancer is the most common cause of cancer death with high morbidity and mortality, which non‐small‐cell lung cancer (NSCLC) accounting for the majority. Traditional Chinese Medicine (TCM) is effective in the treatment of complex diseases, especially cancer. However, TCM is still in the conceptual stage. The interaction between different components
Xing Su +10 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2016, Issue 1, 2016., 2016 Traditional Chinese medicine (TCM) still needs more scientific rationale to be proven for it to be accepted further in the West. We are now in the position to propose computational hypotheses for the mode‐of‐actions (MOAs) of 45 TCM therapeutic action (sub)classes from in silico target prediction algorithms, whose target was later annotated with Kyoto ...
Siti Zuraidah Mohamad Zobir +7 more
wiley +1 more source
Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease
Oxidative Medicine and Cellular Longevity, Volume 2024, Issue 1, 2024.Approximately 70% of all strokes occur in patients over 65 years old, and stroke increases the risk of developing dementia. The circle of Willis (CoW), the ring of arteries at the base of the brain, links the intracerebral arteries to one another to maintain adequate cerebral perfusion.
Vikram Subramanian +6 more
wiley +1 more source