Effects of Lipid Composition on Membrane Permeabilization by Sticholysin I and II, Two Cytolysins of the Sea Anemone Stichodactyla helianthus [PDF]
Biophysical Journal, 2001 Sticholysin I and II (St I and St II), two basic cytolysins purified from the Caribbean sea anemone Stichodactyla helianthus, efficiently permeabilize lipid vesicles by forming pores in their membranes.
Mauro Dalla Serra +2 more
exaly +3 more sources
Functional and Structural Variation among Sticholysins, Pore-Forming Proteins from the Sea Anemone Stichodactyla helianthus [PDF]
Int J Mol Sci, 2020 Venoms constitute complex mixtures of many different molecules arising from evolution in processes driven by continuous prey–predator interactions. One of the most common compounds in these venomous cocktails are pore-forming proteins, a family of toxins
Esperanza Rivera-de-Torre +5 more
semanticscholar +2 more sources
Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. [PDF]
PLoS ONE, 2023 Targeting the Kv1.3 potassium channel has proven effective in reducing obesity and the severity of animal models of autoimmune disease. Stichodactyla toxin (ShK), isolated from the sea anemone Stichodactyla helianthus, is a potent blocker of Kv1.3 ...
Yuqing Wang +7 more
doaj +4 more sources
Multiple ShKT domain-containing MUL-1 proteins act as redox-responsive modulators of oxidative stress signaling in C. elegans [PDF]
Molecules and Cells: Organismal survival depends on coordinated responses to oxidative stress and DNA damage. Using Caenorhabditis elegans, we investigate mul-1, a robust transcriptional target of ionizing radiation and reactive oxygen species.
Emilio Carranza-García +3 more
doaj +2 more sources
Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family [PDF]
BMC Biology, 2023 Background The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in Actiniarians remain uncharacterised. One such peptide family, sea anemone 8 (SA8),
Lauren M. Ashwood +22 more
doaj +2 more sources
Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus. [PDF]
Acta Crystallogr Sect F Struct Biol Cryst Commun, 2012 R. García-Fernández +8 more
semanticscholar +2 more sources
Two-dimensional crystallization on lipid monolayers and three-dimensional structure of sticholysin II, a cytolysin from the sea anemone Stichodactyla helianthus. [PDF]
Biophys J, 2000 Jaime Martı́n-Benito +5 more
semanticscholar +2 more sources