Results 41 to 50 of about 461 (139)

Purification and Characterization of Gigantoxin-4, a New Actinoporin from the Sea Anemone Stichodactyla Gigantea

International Journal of Biological Sciences, 2011
A new Cytolysin, termed as Gigantoxin-4, was isolated from the sea anemone Stichodactyla gigantea and found to be highly homologous with Cytolysin-3 (HMg III) from Heteractis magnifica, RTX-A from Radianthus macrodactylus, and Sticholysin-1 (St I) and ...
Bo Hu, Wei Guo, Liang-hua Wang, Jian-guang Wang, Xiao-yu Liu, Bing-hua Jiao
doaj  

Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: Their interaction with membranes

Toxicon, 2009
Sticholysins (Sts) I and II (StI/II) are pore-forming toxins (PFTs) produced by the Caribbean Sea anemone Stichodactyla helianthus belonging to the actinoporin family, a unique class of eukaryotic PFTs exclusively found in sea anemones. As for the rest of the members of this family, Sts are cysteine-less proteins, with molecular weights around 20 kDa ...
Carlos, Alvarez, José M, Mancheño, Diana, Martínez, Mayra, Tejuca, Fabiola, Pazos, María E, Lanio   +5 more
openaire   +2 more sources

Construction of an immunotoxin by linking a monoclonal antibody against the human epidermal growth factor receptor and a hemolytic toxin

Biological Research, 2007
Hybrid molecules obtained through conjugation of monoclonal antibodies and toxins constitute an approach under exploration to generate potential agents for the treatment of cancer and other diseases.
ANA D AVILA, CARLOS F CALDERÓN, RITA M PEREZ, CARMEN PONS, CELIA M PEREDA, ANA R ORTIZ   +5 more
doaj  

Stycholysin II, a cytolysin from the sea anemone Stichodactyla helianthus promotes higher hemolysis in aged red blood cells

Toxicon, 2008
We have investigated the relationship between the status of red blood cells (RBCs) and their susceptibility to toxin sticholysin II (StII) hemolytic activity; we have evaluated this effect in different RBC ensembles, comprising young and old cells, and in cells partially damaged by their pre-exposition to a free radical source.
Celedon, Gloria, Gonzalez, Gustavo, Barrientos, Daniela, Pino, Jose, Venegas, Fabiola, Lissi, Eduardo A., Soto, Carmen, Martinez, Diana, Alvarez, Carlos, Lanio, Maria Eliana   +9 more
openaire   +4 more sources

Separation and characterization of four different amino acid sequence variants of a sea anemone (Stichodactyla helianthus) protein cytolysin

Toxicon, 1988
A basic protein cytolysin previously isolated from the Caribbean sea anemone Stichodactyla helianthus was shown by CM cellulose chromatography to consist of four isotoxins possessing different N-terminal amino acid sequences. These are designated as toxins I-IV in order of increasing isoelectric point.
Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, U.S.A. ( host institution ), Kem, William R., Dunn, Ben M.   +2 more
openaire   +3 more sources

Bioprospecting of Sea Anemones (Cnidaria, Anthozoa, Actiniaria) for β-Defensin-like α-Amylase Inhibitors. [PDF]

Biomedicines, 2023
Popkova D, Otstavnykh N, Sintsova O, Baldaev S, Kalina R, Gladkikh I, Isaeva M, Leychenko E.   +7 more
europepmc   +1 more source

Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families. [PDF]

Mar Drugs, 2023
Pascual Alonso I, Almeida García F, Valdés Tresanco ME, Arrebola Sánchez Y, Ojeda Del Sol D, Sánchez Ramírez B, Florent I, Schmitt M, Avilés FX.   +8 more
europepmc   +1 more source

Esters biotransformation by immobilized interfacial esterases from the Caribbean Sea anemone : Stichodactyla helianthus

, 2015
An immobilized biocatalyst (ShIE-Octyl) was obtained by interfacial adsorption on Octyl-Sepharose CL 4B sup-port of all interfacial esterases from the aqueous extract of the sea anemone Stichodactyla helianthus. ShIE-Octyl, synthesized by this simple method, contains semipurified interfacial esterases, including the isotoxins StI and StII.
Monte-Martínez, Alberto del, González-Bacerio, J., Cutiño-Avila, Bessy, Ruiz, R., Ávila, R., Ramos-Leal, M., Nolasco, H., Díaz, J., Guisán, José Manuel   +8 more
openaire   +1 more source

The Mitochondrial Genome of the Sea Anemone Stichodactyla haddoni Reveals Catalytic Introns, Insertion-Like Element, and Unexpected Phylogeny. [PDF]

Life (Basel), 2021
Johansen SD, Chi SI, Dubin A, Jørgensen TE.   +3 more
europepmc   +1 more source

Multiomic Approach for Bioprospection: Investigation of Toxins and Peptides of Brazilian Sea Anemone Bunodosoma caissarum. [PDF]

Mar Drugs, 2023
Mazzi Esquinca ME, Correa CN, Marques de Barros G, Montenegro H, Mantovani de Castro L.   +4 more
europepmc   +1 more source