Fighting the global pest problem: Preface to the special Toxicon issue on insecticidal toxins and their potential for insect pest control [PDF]
, 2007 Arthropod pests are responsible for major crop devastation and are vectors for the transmission of new and re-emerging diseases in humans and livestock.
Nicholson, GM
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Toxicon, 1988 A basic protein cytolysin previously isolated from the Caribbean sea anemone Stichodactyla helianthus was shown by CM cellulose chromatography to consist of four isotoxins possessing different N-terminal amino acid sequences. These are designated as toxins I-IV in order of increasing isoelectric point.
Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, U.S.A. ( host institution ) +2 more
openaire +3 more sources
Modulation of T and B cell function in Granulomatosis with polyangiitis:Targeting Kv1.3 potassium channels [PDF]
, 2019 Granulomatosis with polyangiitis (GPA) is a chronic systemic autoimmune disease characterized by inflammation of small blood vessels predominantly in the upper and lower respiratory tract and/or kidney.
Lintermans, Lucas Leonard
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Conformational exchange in the potassium channel blocker ShK [PDF]
, 2019 ShK is a 35-residue disulfide-linked polypeptide produced by the sea anemone Stichodactyla helianthus, which blocks the potassium channels Kv1.1 and Kv1.3 with pM affinity. An analogue of ShK has been developed that blocks Kv1.3 > 100 times more potently
Baxter, N.J. +7 more
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Development of a StIW111C-based bioresponsive pore-forming conjugate for permeabilizing the endosomal membrane [PDF]
Gene expression manipulation is pivotal in therapeutic approaches for various diseases. Non-viral delivery systems present a safer alternative to viral vectors, with reduced immunogenicity and toxicity. However, their effectiveness in promoting endosomal
Alvarez, Carlos +13 more
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Bioprospecting of Sea Anemones (Cnidaria, Anthozoa, Actiniaria) for β-Defensin-like α-Amylase Inhibitors. [PDF]
Biomedicines, 2023 Popkova D +7 more
europepmc +1 more source
Structural and functional characterization of venom pore forming proteins [PDF]
, 2021 Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, Departamento de Bioquímica y Biología Molecular, leída el 11-12-2020.Las proteínas formadoras de poros (PFP) son una familia de toxinas capaces de matar células por ...
Rivera de Torre, Esperanza
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Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families. [PDF]
Mar Drugs, 2023 Pascual Alonso I +8 more
europepmc +1 more source