Results 71 to 80 of about 7,385 (298)

Numerical solution of stiff systems of differential equations arising from chemical reactions [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization, 2014
Long time integration of large stiff systems of initial value problems, arising from chemical reactions, demands efficient methods with good accuracy and extensive absolute stability region.
Gholamreza Hojjati   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Overlapping operator splitting methods andapplications in stiff differential equations [PDF]

open access: yes, 2008
In this article we study the stability of an overlapping operatorsplitting methods based on iterative methods. We discuss the overlapping iterative Operator Splitting method in the context of decoupling the stiff and non-stiff operators.
Geiser, Jürgen
core   +1 more source

On overcoming Dahlquist’s second barrier for$A$-stable linear multistep methods [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
Dahlquist’s second barrier limits the order of $A$-stable linear multistep methods to at most two, posing significant challenges for achieving higher accuracy in the numerical solution of stiff ordinary differential equations.
G. Hojjati, S. Fazeli, A. Moradi
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Numerical methods for ordinary differential equations with applications to partial differential equations

open access: yes, 1983
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The thesis develops a number of algorithms for the numerical solution of ordinary differential equations with applications to partial differential equations.
Khaliq, Abdul Qayyum Masud
core  

Implicit Taylor methods for stiff stochastic differential equations

open access: yes, 2001
In this paper we discuss implicit Taylor methods for stiff Itô stochastic differential equations. Based on the relationship between Itô stochastic integrals and backward stochastic integrals, we introduce three implicit Taylor methods: the implicit Euler–
Kevin Burrage   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An introduction to regular splines and their application for initial value problems of ordinary differential equations

open access: yes, 1975
This report describes an application of the general method of integrating initial value problems by means of regular splines for equations with movable singularities.
Werner, H
core  

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