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Matrix Stiffness: the Conductor of Organ Fibrosis
Current Rheumatology Reports, 2018Organ fibrosis is a lethal component of scleroderma. The hallmark of scleroderma fibrosis is extensive extracellular matrix (ECM) deposition by activated myofibroblasts, specialized hyper-contractile cells that promote ECM remodeling and matrix stiffening.
Alba, Santos, David, Lagares
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Extracellular Matrix Stiffness in Lung Health and Disease
Comprehensive Physiology, 2022Abstract The extracellular matrix (ECM) provides structural support and imparts a wide variety of environmental cues to cells. In the past decade, a growing body of work revealed that the mechanical properties of the ECM, commonly known as matrix stiffness, regulate the fundamental cellular processes of the lung ...
Ting, Guo +3 more
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Stiffness Matrix of Compliant Parallel Mehanisms
Volume 2: 32nd Mechanisms and Robotics Conference, Parts A and B, 2008Starting from the definition of a stiffness matrix, the authors present the Cartesian stiffness matrix of parallel compliant mechanisms. The proposed formulation is more general than any other stiffness matrix found in the literature since it can take into account the stiffness of the passive joints and remains valid for large displacements.
C. Quennouelle, C. M. Gosselin
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Affine connections for the Cartesian stiffness matrix
Proceedings of International Conference on Robotics and Automation, 2002We study the 6/spl times/6 Cartesian stiffness matrix. We show that the stiffness of a rigid body subjected to conservative forces and moments is described by a (0,2) tensor which is the Hessian of the potential function. The key observation of the paper is that since the Hessian depends on the choice of an affine connection in the task space, so will ...
Milos Zefran, Vijay Kumar 0001
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2009
Matrix stiffness method (MSM) is a modern powerful method of analysis of engineering structures. Its effective and widespread application is associated with availability of modern computers and effective computer programs. The MSM allows performing detail analysis of any sophisticated 2D and 3D engineering structure and takes into account different ...
Igor A. Karnovsky, Olga Lebed
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Matrix stiffness method (MSM) is a modern powerful method of analysis of engineering structures. Its effective and widespread application is associated with availability of modern computers and effective computer programs. The MSM allows performing detail analysis of any sophisticated 2D and 3D engineering structure and takes into account different ...
Igor A. Karnovsky, Olga Lebed
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Recovering Mesh Geometry from a Stiffness Matrix
Numerical Algorithms, 2002zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Andreas Stathopoulos, Shang-Hua Teng
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Element Stiffness Matrix Generator
Journal of the Structural Division, 1971This paper presents the basic concepts required to construct a computer code capable of deriving element stiffness matrices. The computer program requires only the displacement functions, transformation matrices, and a few control cards as input.
Richard H. Gunderson, Ayhan Cetiner
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1997
This introduction to stiffness matrices will show how to derive the appropriate matrix connecting ‘force’ to ‘displacement’ for (i) a bar under uniaxial stressing, (ii) a beam in bending and (iii) a shaft under torsion, using the work of previous chapters.
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This introduction to stiffness matrices will show how to derive the appropriate matrix connecting ‘force’ to ‘displacement’ for (i) a bar under uniaxial stressing, (ii) a beam in bending and (iii) a shaft under torsion, using the work of previous chapters.
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Arterial Stiffness and Extracellular Matrix
2006The growing prevalence and associated risk of arterial stiffness provide a major challenge to better understand the underlying causes and the resultant physiological impact of this condition. Structural components within the arterial wall, mainly collagen and elastin, are considered to be major determinants of arterial stiffness. Thus, quantitative and
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Matrix-Free Methods for Stiff Systems of ODE’s
SIAM Journal on Numerical Analysis, 1986The popular backward differentiation methods for solving stiff systems of ordinary differential equations, being implicit, require the solution of a linear algebraic system at each time step. The coefficient matrix is closely related to the Jacobian matrix of the differential system, and large systems may require considerable storage for the Jacobian ...
Brown, Peter N., Hindmarsh, Alan C.
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